Department of Chemistry, Jadavpur University, Kolkata 700032, West Bengal, India.
Org Biomol Chem. 2019 Feb 27;17(9):2321-2325. doi: 10.1039/c8ob03033b.
A general and efficient synthesis of diverse tetracyclic indolo[2,3-b]quinoline derivatives was achieved through palladium-catalyzed domino carboannulation/cross-coupling and DDQ-mediated double cross-dehydrogenative C-N bond formation. This approach provides a straightforward, atom-economical and concise route to easily access a diverse range of tetracyclic indolo[2,3-b]quinolines and their analogues in excellent yields with good tolerance of functional groups.
通过钯催化的串联碳环化/交叉偶联和 DDQ 介导的双重交叉脱氢 C-N 键形成，实现了多种四环吲哚并[2,3-b]喹啉衍生物的通用、高效合成。该方法提供了一条直接、原子经济性和简洁的路线，可在良好的官能团容忍度下，以优异的收率轻松获得各种四环吲哚并[2,3-b]喹啉及其类似物。
