Department of Chemistry, Fudan University, Shanghai, People's Republic of China.
Org Lett. 2011 Mar 4;13(5):1150-3. doi: 10.1021/ol103173v. Epub 2011 Feb 9.
A novel and efficient route for the synthesis of 5H-cyclopenta[c]quinoline derivatives via a palladium-catalyzed domino reaction of o-alkynylhalobenzene with amine is described. The starting materials are easily available, and the reaction proceeds smoothly with high efficiency, which shows broad scope with good functional group tolerance.
通过钯催化邻炔基卤代苯与胺的串联反应，我们描述了一种合成 5H-环戊并[c]喹啉衍生物的新颖、高效途径。该反应的起始原料易得，反应条件温和，具有高效、广泛的官能团容忍度等优点。
