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皮肤镜检查概述及诊断外应用

Dermoscopy Overview and Extradiagnostic Applications

作者信息

Sonthalia Sidharth, Yumeen Sara, Kaliyadan Feroze

机构信息

SKINNOCENCE: The Skin Clinic

Warren Alpert Medical School of Brown University

Abstract

Cutaneous diagnosis is often, but not always, visually based. Dermatologists tend to encounter situations where the possibility of multiple differentials complicates the diagnosis and mandates investigations for confirmation. Methods commonly employed for cutaneous diagnosis may be invasive (skin and scalp biopsy), semi-invasive (slit skin smears, trichogram, etc.) or non-invasive (e.g., KOH smear, nail clipping, hair count for hair loss). Dermoscopy, also known as epiluminescence microscopy, or skin surface microscopy, is a non-invasive, technique, which has traditionally found use in the evaluation and differentiation of suspicious melanocytic lesions from dysplastic lesions and melanomas, as well as keratinocyte skin cancers such as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Over the last several years, the use of dermoscopy has been increasing in the context of general dermatological disorders including inflammatory dermatosis, pigmentary dermatosis, infectious dermatosis, and disorders of the hair, scalp, and nails. Some terms are used to describe specific indications: pigmentaroscopy for pigmented lesions, trichoscopy of the scalp and hair, onychoscopy of the nails, inflammoscopy for inflammatory dermatosis and lesions, as well as entomodermoscopy of skin infestations and infections . The role of dermoscopy in diagnosing disorders of general dermatology has undergone elaborate discussion . In this chapter, we shall review the plethora of extra-diagnostic indications of this technique and highlight technical aspects worth considering.

摘要

皮肤诊断通常(但并非总是)基于视觉。皮肤科医生常常会遇到多种鉴别诊断可能性使诊断复杂化并需要进行检查以确诊的情况。常用于皮肤诊断的方法可能是侵入性的(皮肤和头皮活检)、半侵入性的(皮肤刮片、毛发检查等)或非侵入性的(例如,氢氧化钾涂片、指甲剪取、脱发的毛发计数)。皮肤镜检查,也称为落射荧光显微镜检查或皮肤表面显微镜检查,是一种非侵入性技术,传统上用于评估和鉴别可疑黑素细胞病变与发育异常病变及黑色素瘤,以及角化细胞皮肤癌,如基底细胞癌(BCC)和鳞状细胞癌(SCC)。在过去几年中,皮肤镜检查在包括炎症性皮肤病、色素性皮肤病、感染性皮肤病以及毛发、头皮和指甲疾病在内的一般皮肤病的诊断中使用越来越多。一些术语用于描述特定的适应症:色素性病变的色素镜检查、头皮和毛发的毛发镜检查、指甲的甲镜检查、炎症性皮肤病和病变的炎症镜检查,以及皮肤寄生虫感染和感染的昆虫皮肤镜检查。皮肤镜检查在一般皮肤科疾病诊断中的作用已经经过了详细的讨论。在本章中,我们将回顾该技术大量的诊断外适应症,并强调值得考虑的技术方面。

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