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衣原体

Chlamydia

作者信息

Mohseni Michael, Sung Sharon, Rausch-Phung Elizabeth A., Takov Veronica

机构信息

Mayo Clinic

Sparrow Hospital

PMID:30725971
Abstract

Chlamydia is a sexually transmitted infectious disease caused by the bacterium . In the United States, chlamydia is the most commonly reported bacterial infection. Globally, is the most common sexually transmitted infection (STI), and reported rates of infection have been climbing in the last few decades. causes the ocular infection trachoma, which is the leading infectious cause of blindness worldwide. In females, the cervix is the most commonly infected anatomic site. This can manifest as cervicitis, urethritis, pelvic inflammatory disease, perihepatitis, or proctitis. Chlamydial infections in women, especially if untreated, increase the risk of infertility and ectopic pregnancy, leading to high medical costs. Associated risks of chlamydia infection during pregnancy are also present. Additionally, infants born vaginally to mothers infected with genital may develop conjunctivitis or pneumonia. In men, infection with can lead to urethritis, epididymitis, prostatitis, proctitis, or reactive arthritis. Both men and women infected with may also experience conjunctivitis, pharyngitis, and lymphogranuloma venereum (see . Follicular Conjunctivitis). Lymphogranuloma venereum (LGV), caused by distinct serovars of , is a less common disease characterized by enlarged lymph nodes or severe proctocolitis.

摘要

衣原体病是一种由细菌引起的性传播感染疾病。在美国,它是报告最为常见的细菌感染。在全球范围内,它是最常见的性传播感染。它会引发一种名为“沙眼”的眼部感染,沙眼是全球失明的主要感染病因。在女性中,子宫颈是最常被感染的解剖部位。这可能表现为宫颈炎、尿道炎、盆腔炎、肝周围炎或直肠炎。女性的衣原体感染,尤其是未经治疗的情况下,会增加不孕和异位妊娠的风险,导致高昂的医疗费用。如果女性在怀孕期间感染也存在风险。此外,通过阴道分娩的婴儿若其母亲感染了生殖道衣原体,可能会患上结膜炎和/或肺炎。在男性中,衣原体感染可导致尿道炎、附睾炎、前列腺炎、直肠炎或反应性关节炎。感染衣原体的男性和女性也可能会出现结膜炎、咽炎和性病性淋巴肉芽肿。性病性淋巴肉芽肿(LGV)由衣原体的不同血清型引起,是一种不太常见的疾病,其特征为淋巴结肿大或严重的直肠结肠炎。