Madassery Sreekumar
Division of Vascular and Interventional Radiology, Rush University Medical Center, Rush Oak Park Hospital, Chicago, Illinois.
Semin Intervent Radiol. 2018 Dec;35(5):461-468. doi: 10.1055/s-0038-1676091. Epub 2019 Feb 5.
Endovascular recanalization for patient with peripheral arterial disease and the end of its spectrum critical limb ischemia (CLI) has become a preferred method of revascularization due to advancement of techniques and equipment, allowing reduction of limb amputations while maintaining a minimally invasive approach compared to surgical approaches. Interventionalists have undertaken a progressively increasing complexity of diseased vessels in the hopes of providing inline unobstructed flow through occlusions for patients with claudication as well as direct flow to a nonhealing wound in patients with CLI. One of the major roadblocks encountered in lower extremity recanalization procedures is managing severely calcified chronic thrombotic occlusions which decrease luminal revascularization, ultimately increasing use of adjunctive interventions such as subintimal tracking, reentry device utilization, and stent placement. Understanding the histopathology and classification of lower extremity calcifications, imaging findings, and escalation of equipment use provides a thorough background in dealing with these specific cases.
由于技术和设备的进步,针对外周动脉疾病患者及其最严重阶段——严重肢体缺血(CLI)的血管内再通术已成为血管重建的首选方法,与外科手术方法相比,它在保持微创的同时减少了肢体截肢。介入医生处理的病变血管越来越复杂,希望为间歇性跛行患者提供通过闭塞部位的畅通无阻的直线血流,并为CLI患者的不愈合伤口提供直接血流。下肢再通手术中遇到的主要障碍之一是处理严重钙化的慢性血栓性闭塞,这会降低管腔再血管化,最终增加诸如内膜下跟踪、再入装置使用和支架置入等辅助干预措施的使用。了解下肢钙化的组织病理学和分类、影像学表现以及设备使用的升级,可为处理这些特殊病例提供全面的背景知识。