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由一种不寻常病原体引起的早发型新生儿脑膜炎-。

Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen-.

作者信息

Siwakoti Shraddha, Bajracharya Sohani, Adhikaree Neetu, Sah Rinku, Rajbhandari Rupa Singh, Khanal Basudha

机构信息

Assistant Professor, Department of Microbiology, BP Koirala Institute of Health Sciences, Dharan, Nepal.

Junior Resident, Department of Microbiology, BP Koirala Institute of Health Sciences, Dharan, Nepal.

出版信息

Case Rep Pediatr. 2019 Jan 9;2019:4740504. doi: 10.1155/2019/4740504. eCollection 2019.

DOI:10.1155/2019/4740504
PMID:30729056
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6343129/
Abstract

INTRODUCTION

are part of the normal flora of the human respiratory tract and are known to have low pathogenic potential. The organism is rarely reported in the literature as the causative agent of meningitis. We report the first case of early-onset neonatal meningitis associated with from Nepal.

CASE REPORT

A 3-day-old baby with fever and yellowish discolouration of the body since 48 hrs was admitted to the neonatal ward. The baby developed 3 episodes of seizures in the form of uprolling of eyes on the first day of admission during phototherapy course for raised serum bilirubin. Sepsis screen was positive, and meningitis was confirmed as the cerebrospinal fluid culture grew Cranial ultrasound scan was normal. The baby received a 21-day course of intravenous cefotaxime and amikacin. Recovery has been uneventful to date.

CONCLUSION

Neonatal meningitis is a life-threatening infection. This case report presents an uncommon aetiology of neonatal meningitis which can be misidentified in the diagnostic bacteriology laboratory in resource constraints area like ours.

摘要

引言

是人类呼吸道正常菌群的一部分,已知致病潜力较低。该生物体作为脑膜炎的病原体在文献中很少被报道。我们报告了尼泊尔首例与相关的早发性新生儿脑膜炎病例。

病例报告

一名3天大的婴儿自48小时以来出现发热和身体发黄,被收入新生儿病房。该婴儿在因血清胆红素升高进行光疗期间,入院第一天出现3次眼球上翻形式的癫痫发作。败血症筛查呈阳性,脑脊液培养生长确诊为脑膜炎。头颅超声扫描正常。该婴儿接受了为期21天的静脉注射头孢噻肟和阿米卡星治疗。迄今为止恢复顺利。

结论

新生儿脑膜炎是一种危及生命的感染。本病例报告呈现了新生儿脑膜炎一种不常见的病因,在我们这样资源有限的地区的诊断细菌学实验室中可能会被误诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e58a/6343129/3074a114d4d6/CRIPE2019-4740504.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e58a/6343129/3074a114d4d6/CRIPE2019-4740504.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e58a/6343129/3074a114d4d6/CRIPE2019-4740504.001.jpg

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Bacterial meningitis in children under 15 years of age in Nepal.尼泊尔15岁以下儿童的细菌性脑膜炎
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Moraxella catarrhalis, a human respiratory tract pathogen.卡他莫拉菌,一种人类呼吸道病原体。
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Neonatal meningitis due to Moraxella catarrhalis and review of the literature.卡他莫拉菌所致新生儿脑膜炎及文献复习
Ann Trop Paediatr. 1996 Sep;16(3):199-201. doi: 10.1080/02724936.1996.11747826.