Quality of life Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, No.146, South Gandi Ave, Vanak Sq, Tehran, 1517964311, Iran.
Integrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, No.146, South Gandi Ave, Vanak Sq, Tehran, 1517964311, Iran.
Support Care Cancer. 2019 Oct;27(10):3805-3811. doi: 10.1007/s00520-019-04681-9. Epub 2019 Feb 7.
We aimed to determine the effectiveness of combined decongestive therapy (CDT) and the minimum sessions required to significantly reduce pain and heaviness in patients with breast cancer-related lymphedema.
A sample of 169 patients with breast cancer-related lymphedema underwent CDT, 5 days/week for a total of 3 to 4 weeks. Self-reported pain and heaviness was quantified on a separate visual analog scale (VAS) prior to CDT and after 3, 5, 7, 10, and 15 sessions. Scores derived from VASs were categorized into three categories: mild (score < 4), moderate (score = 4-6), and severe (score > 6). Downward transition for at least one category in severity of each parameter was considered as an improvement. Repeated measure analysis of variance was conducted to test the effect of time on the severities of pain and heaviness while age, afflicted side with lymphedema, history of chemotherapy, and radiotherapy were considered as covariates.
The mean age of patients was 52.66 ± 12.20 years. In all 132 patients, out of 169 patients (71.3%) reported pain and 155 patients (83.7%) reported heaviness at baseline. However, after intervention, the cumulative percentage of patients with at least a one category reduction in pain and heaviness was 86.4% and 83%, respectively. At least seven sessions of CDT were shown to be sufficient in alleviating the severity of the symptoms in greater than 83% of patients.
The combined decongestive therapy significantly reduced the intensities of pain and heaviness in patients with breast cancer-related lymphedema.
我们旨在确定联合减压疗法(CDT)的有效性,以及显著减轻乳腺癌相关淋巴水肿患者疼痛和沉重感所需的最少疗程。
169 例乳腺癌相关淋巴水肿患者接受 CDT,每周 5 天,总共 3 至 4 周。在 CDT 之前和之后的 3、5、7、10 和 15 个疗程后,使用单独的视觉模拟量表(VAS)量化自我报告的疼痛和沉重感。从 VAS 获得的评分分为三个类别:轻度(评分<4)、中度(评分=4-6)和重度(评分>6)。至少一个参数的严重程度下降一个类别被认为是改善。进行重复测量方差分析以检验时间对疼痛和沉重感严重程度的影响,同时考虑年龄、淋巴水肿受累侧、化疗和放疗史作为协变量。
患者的平均年龄为 52.66±12.20 岁。在所有 132 例患者中,169 例患者中有 132 例(71.3%)报告疼痛,155 例(83.7%)报告沉重感。然而,在干预后,疼痛和沉重感至少降低一个等级的患者累积百分比分别为 86.4%和 83%。至少进行 7 次 CDT 即可缓解 83%以上患者症状的严重程度。
联合减压疗法可显著减轻乳腺癌相关淋巴水肿患者的疼痛和沉重感强度。