Gasser Jürg Andreas, Willnecker Johannes
Department of Musculoskeletal Diseases, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Stratec Medizintechnik GmbH, Pforzheim, Germany.
Methods Mol Biol. 2019;1914:533-558. doi: 10.1007/978-1-4939-8997-3_29.
This chapter provides information for the in vivo use of peripheral quantitative computed tomography in rats and mice to determine bone density and cortical geometric data, including suggestions for study design, instrument setting, and data interpretation. This update also provides guidance for the use of pQCT to extract muscle and fat cross-sectional area information from the bone scans.
本章提供了关于在大鼠和小鼠体内使用外周定量计算机断层扫描来测定骨密度和皮质骨几何数据的信息,包括研究设计、仪器设置和数据解读的建议。本次更新还提供了使用外周定量计算机断层扫描从骨扫描中提取肌肉和脂肪横截面积信息的指导。