Milyani Asmaa Adel, Al-Agha Abdulmoein Eid
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Paediatrics, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Ann Afr Med. 2019 Jan-Mar;18(1):42-46. doi: 10.4103/aam.aam_17_18.
The objectives of this study were to study the relationship between lipid profile components among different body mass index (BMI) groups and investigate the association between gender and BMI.
This cross-sectional study included 218 children and adolescents; 104 males and 114 females. Accepted age range was from 2 to 18 years. Data were collected from February to May during the year of 2017 and were analyzed using the Statistical Package for the Social Sciences. Standard deviation (SD) for BMI was calculated based on the World Health Organization guidelines. Lipid profile results were reviewed from laboratory reports.
Nearly 10.6% of the study population were found to be overweight; another 22.1% were suffering from obesity, of which 7.1% were morbidly obese. Children who had high levels of low-density lipoprotein (LDL) and low levels of high-density lipoprotein (HDL) were found among higher BMI groups, with elevated cholesterol levels noted in patients of increased weight. An increase in HDL levels was noted in 71% of the children who avoided fast-food consumption. Significant gender predisposition to changes in BMI was not found (P = 0.467).
High BMI was found to be associated with increased levels of LDL cholesterol and decreased levels of HDL cholesterol. No significant association between gender and changes in lipid profile was established (P = 0.898).
All pediatricians must keep an open eye on overweight and obese children, routinely taking their weight measurements and screening for dyslipidemia by obtaining a full lipid profile for every child whose weight is 2 SDs above the mean.
本研究的目的是探讨不同体重指数（BMI）组之间血脂谱成分的关系，并研究性别与BMI之间的关联。
这项横断面研究纳入了218名儿童和青少年；其中104名男性和114名女性。接受的年龄范围为2至18岁。数据于2017年2月至5月收集，并使用社会科学统计软件包进行分析。BMI的标准差（SD）根据世界卫生组织指南计算。血脂谱结果从实验室报告中进行回顾。
研究人群中近10.6%被发现超重；另有22.1%患有肥胖症，其中7.1%为病态肥胖。在较高BMI组中发现低密度脂蛋白（LDL）水平高和高密度脂蛋白（HDL）水平低的儿童，体重增加的患者胆固醇水平升高。在71%避免食用快餐的儿童中发现HDL水平有所升高。未发现BMI变化存在显著的性别倾向（P = 0.467）。
发现高BMI与LDL胆固醇水平升高和HDL胆固醇水平降低有关。未确立性别与血脂谱变化之间的显著关联（P = 0.898）。
所有儿科医生必须密切关注超重和肥胖儿童，定期测量他们的体重，并通过为每个体重高于平均水平2个标准差的儿童进行完整的血脂谱筛查来检测血脂异常。
