Institute of Developmental Biology and Neurobiology, Johannes Gutenberg University of Mainz, Germany.
Institute of Physiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Neuron. 2019 Feb 6;101(3):356-357. doi: 10.1016/j.neuron.2019.01.032.
In this issue of Neuron, Spitzer et al. (2019) demonstrate age- and region-dependent diversity in the expression of voltage-gated ion channels and neurotransmitter receptors in oligodendrocyte progenitors. These define their interactions with neurons and thus suggest an increasing functional heterogeneity with age and between brain regions.
在本期《神经元》杂志中,Spitzer 等人(2019)表明,少突胶质前体细胞中电压门控离子通道和神经递质受体的表达具有年龄和区域依赖性的多样性。这些多样性定义了它们与神经元的相互作用,因此表明随着年龄的增长和大脑区域的不同,功能异质性逐渐增加。