Aramburu Jorge, Antón Raúl, Rivas Alejandro, Ramos Juan Carlos, Larraona Gorka S, Sangro Bruno, Bilbao José Ignacio
a Universidad de Navarra , TECNUN Escuela de Ingenieros , Donostia-San Sebastián , Spain.
b Instituto de Investigación Sanitaria de Navarra (IdiSNA) , Pamplona , Spain.
Comput Methods Biomech Biomed Engin. 2019 Apr;22(5):518-532. doi: 10.1080/10255842.2019.1567720. Epub 2019 Feb 7.
Balloon-occluded transarterial chemoembolisation (B-TACE) is an intraarterial transcatheter treatment for liver cancer. In B-TACE, an artery-occluding microballoon catheter occludes an artery and promotes collateral circulation for drug delivery to tumours. This paper presents a methodology for analysing the haemodynamics during B-TACE, by combining zero-dimensional and three-dimensional modelling tools. As a proof of concept, we apply the methodology to a patient-specific hepatic artery geometry and analyse two catheter locations. Results show that the blood flow redistribution can be predicted in this proof-of-concept study, suggesting that this approach could potentially be used to optimise catheter location.
球囊闭塞经动脉化疗栓塞术（B-TACE）是一种用于治疗肝癌的动脉内导管治疗方法。在B-TACE中，一种动脉闭塞微球囊导管可阻塞动脉，并促进侧支循环以将药物输送至肿瘤。本文提出了一种通过结合零维与三维建模工具来分析B-TACE期间血流动力学的方法。作为概念验证，我们将该方法应用于特定患者的肝动脉几何结构，并分析了两种导管位置。结果表明，在该概念验证研究中可以预测血流再分布，这表明该方法可能潜在地用于优化导管位置。
