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经微创管状入路切除小脑血管母细胞瘤。

Resection of a cerebellar hemangioblastoma via a minimally invasive tubular approach.

作者信息

Krüger Marie T, Klingler Jan-Helge

机构信息

Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

出版信息

J Clin Neurosci. 2019 May;63:240-243. doi: 10.1016/j.jocn.2019.01.045. Epub 2019 Feb 4.

DOI:10.1016/j.jocn.2019.01.045
PMID:30732985
Abstract

Hemangioblastomas are rare benign, highly vascularized tumors occurring in the cerebellum and the spinal cord. They often develop tumor-associated cysts multiple times the size of the solid part of the tumor. Patients with von Hippel-Lindau (VHL) disease typically exhibit multiple tumors with the need of repeated surgeries during their lifetime. As multiple surgeries involve an increased risk of access-related morbidity, a minimally invasive approach can be favorable for specific types of tumors in the posterior fossa. We here present the case of a minimally invasive removal of a superficial cerebellar hemangioblastoma with tumor-associated cyst and indicate the potential benefits and limitations of this technique.

摘要

血管母细胞瘤是罕见的良性、高度血管化肿瘤,发生于小脑和脊髓。它们常多次形成大小为肿瘤实体部分数倍的肿瘤相关囊肿。患有冯·希佩尔-林道(VHL)病的患者通常会出现多个肿瘤,一生中需要多次手术。由于多次手术会增加与手术入路相关的发病风险,对于后颅窝特定类型的肿瘤,微创方法可能更有利。我们在此介绍一例微创切除伴有肿瘤相关囊肿的浅表小脑血管母细胞瘤的病例,并指出该技术的潜在益处和局限性。

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引用本文的文献

1
Hemangioblastoma and von Hippel-Lindau disease: genetic background, spectrum of disease, and neurosurgical treatment.血管母细胞瘤和 von Hippel-Lindau 病:遗传背景、疾病谱及神经外科治疗。
Childs Nerv Syst. 2020 Oct;36(10):2537-2552. doi: 10.1007/s00381-020-04712-5. Epub 2020 Jun 7.