Ravina Kristine, Strickland Ben A, Rennert Robert C, Bakhsheshian Joshua, Russin Jonathan J, Giannotta Steven L
Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United Sates.
J Neurol Surg B Skull Base. 2019 Feb;80(1):31-39. doi: 10.1055/s-0038-1661348. Epub 2018 Jun 29.
To investigate risk factors for symptom recurrence in patients requiring a revision microvascular decompression (MVD) for trigeminal neuralgia (TN) or hemifacial spasm (HFS). Retrospective review of a prospectively maintained database. Seventeen consecutive patients undergoing revision MVD at our institution between January 1993 and September 2017. The incidence and causes for revision MVDs were recorded. Response to revision MVD for TN was tracked using the Barrow Neurological Institute (BNI) grading scale. Response to revision MVD for HFS was graded as "no improvement," "some relief," or "complete resolution" of symptoms. Revision MVD rate for the senior author across all MVDs performed in this period was 1.9% for TN and 9.3% for HFS. Initial MVD failure was primarily caused by active inflammation and/or scarring and adhesions in 5/17 patients, malposition/slippage of Teflon in 3/17 patients, and insufficient Teflon in 1/17 patients. Without other factors, a new site of neurovascular conflict was identified in 4/17 patients, while the same site of neurovascular conflict was found in 3/17 patients. No cause could be identified in 1/17 patients. Scarring was found primarily in the TN group and was associated with symptom persistence. Revision MVD for recurrent TN and HFS is an effective procedure offering the prospect of a complete cure. Proper Teflon use is crucial for surgical success. Scarring after initial MVD is a negative prognostic factor requiring destructive treatment consideration. Although morbidity rates were slightly increased with revision versus original MVDs, the complications were non-disabling and resolved over time.
为了研究三叉神经痛(TN)或面肌痉挛(HFS)患者行微血管减压术(MVD)翻修时症状复发的危险因素。 对前瞻性维护的数据库进行回顾性分析。 1993年1月至2017年9月期间,本机构连续17例患者接受了MVD翻修术。 记录MVD翻修的发生率和原因。采用巴罗神经学研究所(BNI)分级量表追踪TN患者MVD翻修后的反应。HFS患者MVD翻修后的反应分为症状“无改善”、“部分缓解”或“完全缓解”。 在此期间,资深作者进行的所有MVD中,TN的MVD翻修率为1.9%,HFS为9.3%。17例患者中,5例初始MVD失败主要是由于活动性炎症和/或瘢痕形成及粘连,3例是由于聚四氟乙烯位置不当/移位,1例是由于聚四氟乙烯不足。在没有其他因素的情况下,17例患者中有4例发现了新的神经血管冲突部位,17例患者中有3例发现了相同的神经血管冲突部位。17例患者中有1例未发现原因。瘢痕主要见于TN组,与症状持续存在有关。 复发性TN和HFS的MVD翻修是一种有效的手术方法,有望实现完全治愈。正确使用聚四氟乙烯对手术成功至关重要。初始MVD后的瘢痕形成是一个不良预后因素,需要考虑进行破坏性治疗。虽然与初次MVD相比,翻修后的发病率略有增加,但并发症并不致残,且会随时间缓解。