Strijbos Jennifer, van der Linden Yvette M, Vos-Westerman Hanneke, van Baardwijk Angela
MAASTRO Clinic, Department of Radiation Oncology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Leiden University Medical Centre, Department of Radiotherapy, Leiden, The Netherlands.
Clin Transl Radiat Oncol. 2019 Jan 11;15:70-75. doi: 10.1016/j.ctro.2019.01.004. eCollection 2019 Feb.
Palliative radiotherapy (RT) is one of the treatment options for bleeding tumours; a frequent symptom in patients with advanced cancer. The optimal RT schedule is however unclear. This study explores the current pattern of practice of palliative RT for bleeding tumours in the Netherlands.
An internet-based questionnaire, including respondent characteristics, factors influencing the choice of RT schedules and five patient case scenarios, was sent to all members of the Dutch Society for Radiation Oncology. Descriptive statistics were used to evaluate the results.
The response rate was 125/374 (34%); representing 20 out of 21 Dutch RT departments. Most reported influencing factors were performance status, prognosis, patients' comfort and patients' choice. Most preferred RT schedules were 1 × 8 Gy for hematemesis, 1 × 8 Gy and 5 × 4 Gy for haemoptysis, 5 × 4 Gy for haematuria, 5 × 5 Gy for rectal bleeding, 1 × 8 Gy, 5 × 4 Gy and 10-13 × 3 Gy for vaginal bleeding.
The current patterns of practice in the Netherlands for bleeding tumours varied considerably. Most often a single fraction is chosen (35% of all cases), followed by a five-fraction schedule (30% of all cases). The choice of an RT schedule is mainly influenced by patient related factors.
姑息性放疗(RT)是出血性肿瘤的治疗选择之一;这是晚期癌症患者的常见症状。然而,最佳放疗方案尚不清楚。本研究探讨了荷兰出血性肿瘤姑息性放疗的当前实践模式。
向荷兰放射肿瘤学会的所有成员发送了一份基于互联网的问卷,包括受访者特征、影响放疗方案选择的因素以及五个患者病例场景。采用描述性统计来评估结果。
回复率为125/374(34%);代表荷兰21个放疗科室中的20个。报告的最主要影响因素是体能状态、预后、患者舒适度和患者选择。对于呕血,最常用的放疗方案是1×8Gy;咯血为1×8Gy和5×4Gy;血尿为5×4Gy;直肠出血为5×5Gy;阴道出血为1×8Gy、5×4Gy和10 - 13×3Gy。
荷兰目前针对出血性肿瘤的实践模式差异很大。最常选择单次分割(占所有病例的35%),其次是五分割方案(占所有病例的30%)。放疗方案的选择主要受患者相关因素影响。