Garreau C, Garreau-Gomez B, Doumenjou J M
Centre Médical et Thermal Fleur de Gascogne, Barbotan-les-Thermes.
Phlebologie. 1988 Nov-Dec;41(4):857-76.
In the first section, the authors describe some epidemiological features and give an account of the capillary structure and the structure of different veins. They describe the venous physiology and its modulations, in order to be able to give a precise description of different venous affections: venous senescence, chronic venous insufficiency, thrombophlebitis. The particular features of these three pathologies and their action mechanisms enable the authors to envisage appropriate phleboactive therapy, and to evaluate it in advance. As far as the actual notion of evaluating these venous therapies is concerned, the authors make clear that there is no difference between thermal therapies and phleboactive allopathic therapies. They concentrate on describing a unique methodology in two stages considering the thermal establishment as a pharmaceutic laboratory and as an out-patient hospital for follow-up treatment. This therapeutic evaluation comprises two sections: preparation at the laboratory (pharmaco-clinical stage, animal experimentation) and the second stage of therapeutic clinical tests on humans. The authors define a rigorous, quantified methodology based on homogeneous samples in the framework of a computerised medical file consisting of a base and polyvalent satellites. Satellite 3, assembling the elements of the therapeutic form, deals, for example, with phlebotonics, vascular protectors and thermal cures. A detailed list of different phleboactive therapies is drawn up, making it possible to analyse their specific respective effects, and therefore to give specific prescriptions. The patient can hope for preventive measures and a cure with fewer after-effects in the context of a general, well-conducted sanitary education. The authors conclude that patients, doctors and the organizations concerned will benefit greatly from this.
在第一部分中,作者描述了一些流行病学特征,并阐述了毛细血管结构以及不同静脉的结构。他们描述了静脉生理学及其调节机制,以便能够精确描述不同的静脉疾病:静脉衰老、慢性静脉功能不全、血栓性静脉炎。这三种病症的特殊特征及其作用机制使作者能够设想合适的静脉活性疗法,并提前对其进行评估。就评估这些静脉疗法的实际概念而言,作者明确指出热疗法与对抗疗法的静脉活性疗法之间没有区别。他们专注于描述一个分两个阶段的独特方法,将热疗机构视为一个制药实验室和后续治疗的门诊医院。这种治疗评估包括两个部分:实验室准备(药物临床阶段、动物实验)以及对人类进行治疗性临床试验的第二阶段。作者在一个由基础数据库和多用途卫星组成的计算机化医疗档案框架内,基于同质样本定义了一种严格的、量化的方法。卫星3汇集了治疗形式的要素,例如涉及静脉活性药物、血管保护剂和热疗。列出了不同静脉活性疗法的详细清单,从而能够分析它们各自的特定效果,进而开出具体的处方。在全面、良好开展的卫生教育背景下,患者有望获得预防措施以及后遗症较少的治愈方法。作者得出结论,患者、医生和相关组织将从中受益匪浅。