Univ Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Évolutive UMR5558, F-69622 Villeurbanne, France.
Evolution. 2019 Apr;73(4):661-674. doi: 10.1111/evo.13693. Epub 2019 Feb 19.
Recent empirical evidence suggests that trade-off relationships can evolve, challenging the classical image of their high entrenchment. For energy reliant traits, this relationship should depend on the endocrine system that regulates resource allocation. Here, we model changes in this system by mutating the expression and conformation of its constitutive hormones and receptors. We show that the shape of trade-offs can indeed evolve in this model through the combined action of genetic drift and selection, such that their evolutionarily expected curvature and length depend on context. In particular, the shape of a trade-off should depend on the cost associated with resource storage, itself depending on the traded resource and on the ecological context. Despite this convergence at the phenotypic level, we show that a variety of physiological mechanisms may evolve in similar simulations, suggesting redundancy at the genetic level. This model should provide a useful framework to interpret and unify the overly complex observations of evolutionary endocrinology and evolutionary ecology.
最近的实证证据表明，权衡关系可以进化，这挑战了它们高度根深蒂固的经典形象。对于依赖能源的特征，这种关系应该取决于调节资源分配的内分泌系统。在这里，我们通过改变其组成激素和受体的表达和构象来模拟这个系统的变化。我们表明，通过遗传漂变和选择的共同作用，这种权衡关系的形状确实可以在这个模型中进化，使得它们的进化预期曲率和长度取决于环境。特别是，权衡关系的形状应该取决于与资源储存相关的成本，而资源储存本身取决于所交易的资源和生态环境。尽管在表型水平上存在这种趋同，但我们表明，在类似的模拟中可能会进化出多种生理机制，这表明在遗传水平上存在冗余性。这个模型应该为解释和统一进化内分泌学和进化生态学中过于复杂的观察结果提供一个有用的框架。
