Schild Carlos O, Giannitti Federico, Medeiros Rosane M T, da Silva Silveira Caroline, Caffarena Rubén D, Poppenga Robert H, Riet-Correa Franklin
Instituto Nacional de Investigación Agropecuaria (INIA), Plataforma de Investigación en Salud Animal, Estación Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa).
Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay (Schild, Caffarena).
J Vet Diagn Invest. 2019 Mar;31(2):307-310. doi: 10.1177/1040638719831413. Epub 2019 Feb 8.
We describe and illustrate lesions in an outbreak of lead arsenate poisoning in beef cattle that ingested pesticide residues stored in an abandoned building of a former orange orchard. Of 70 exposed cattle, 14 had diarrhea, paresis, ataxia, recumbency, and/or seizures. Ten of the affected animals died after a clinical course of 12-18 h. Pathologic findings in 3 steers included extensive necrohemorrhagic, ulcerative rumenitis, omasitis, and abomasitis; lymphocytolysis in lymphoid organs; and nephrosis. Hepatic arsenic and lead levels in cases 1-3 were 20, 24, and 31 ppm, and 8.3, 25, and 9.4 ppm, respectively. Lesions in the forestomachs and lymphoid tissues have been rarely reported in cases of lead arsenate poisoning. In southern South America, these lesions are indistinguishable from those produced by Baccharis coridifolia, a toxic plant that contains macrocyclic trichothecenes, thus these conditions should be considered in the differential diagnosis of necrotizing lesions in alimentary and lymphoid organs.
我们描述并举例说明了一起肉牛砷酸铅中毒疫情中的病变情况，这些肉牛摄入了储存在一个废弃的原柑橘园建筑中的农药残留。在70头暴露的牛中，14头出现腹泻、轻瘫、共济失调、卧地不起和/或癫痫发作。10头受影响的动物在12 - 18小时的临床病程后死亡。3头阉牛的病理检查结果包括广泛性坏死出血性、溃疡性瘤胃炎、网胃炎和皱胃炎；淋巴器官中的淋巴细胞溶解；以及肾病。病例1 - 3的肝脏砷含量分别为20、24和31 ppm，铅含量分别为8.3、25和9.4 ppm。砷酸铅中毒病例中，前胃和淋巴组织的病变鲜有报道。在南美洲南部，这些病变与含有大环单端孢霉烯族毒素的有毒植物巴卡里斯·科里迪福利亚（Baccharis coridifolia）所造成的病变无法区分，因此在对消化道和淋巴器官坏死性病变进行鉴别诊断时应考虑这些情况。
