Ma L, Tang Z, Chan P, Walston J D
Dr. Jeremy D. Walston, Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA. E-mail:
J Frailty Aging. 2019;8(1):33-38. doi: 10.14283/jfa.2018.38.
Although frailty status greatly impacts health care in countries with rapidly aging populations, little is known about the frailty status in Chinese older adults.
Given the increased health care needs associated with frailty, we sought to develop an easily applied self-report screening tool based on four of the syndromic frailty components and sought to validate it in a population of older adults in China.
Prospective epidemiological cohort study.
Community-dwelling residents living in Beijing, China.
1724 community-dwelling adults aged ≥60 years in 2004 with an 8-year follow up.
We developed a simple self-report frailty screening tool-the Frailty Screening Questionnaire (FSQ)-based on the modified Fried frailty components. The predictive ability for outcome was assessed by age and sex adjusted Cox proportional hazards model.
According to FSQ criteria, 7.1% of the participants were frail. Frailty was associated with poor physical function, fractures, falls, and mortality. Both frailty and pre-frailty were associated with a higher mortality rate: frailty-hazards ratio (HR), 3.94, 95% confidence interval (CI), 3.16-4.92, P<0.001; pre-frailty-HR, 1.89; 95% CI, 1.57-2.27, P <0.001; adjusted models for this variable did not affect the estimates of the association. Among the four frailty components, slowness was the strongest predictor of mortality. The combination of the four components provided the best risk prediction.
FSQ is a self-report frailty measurement tool that can be rapidly performed to identify older adults with higher risk of adverse health outcomes.
尽管在人口快速老龄化的国家，衰弱状态对医疗保健有重大影响，但对于中国老年人的衰弱状态知之甚少。
鉴于与衰弱相关的医疗保健需求增加，我们试图基于衰弱综合征的四个组成部分开发一种易于应用的自我报告筛查工具，并在中国老年人群体中对其进行验证。
前瞻性队列研究。
中国北京的社区居民。
2004年1724名年龄≥60岁的社区居民，随访8年。
我们基于改良的弗里德衰弱组成部分开发了一种简单的自我报告衰弱筛查工具——衰弱筛查问卷（FSQ）。通过年龄和性别调整的Cox比例风险模型评估结果的预测能力。
根据FSQ标准，7.1%的参与者为衰弱。衰弱与身体功能差、骨折、跌倒和死亡率相关。衰弱和衰弱前期均与较高的死亡率相关：衰弱——风险比（HR）为3.94，95%置信区间（CI）为3.16-4.92，P<0.001；衰弱前期——HR为1.89；95%CI为1.57-2.27，P<0.001；该变量的调整模型不影响关联估计。在四个衰弱组成部分中，行动迟缓是死亡率最强的预测因素。四个组成部分的组合提供了最佳的风险预测。
FSQ是一种自我报告的衰弱测量工具，可快速进行，以识别健康不良后果风险较高的老年人。
