a Division of Health Policy and Management, School of Public Health, University of Minnesota , Minneapolis , MN , USA.
b Division of Health Behavior and Health Promotion, College of Public Health, The Ohio State University , Columbus, OH , USA.
Hum Vaccin Immunother. 2019;15(7-8):1897-1903. doi: 10.1080/21645515.2019.1578592. Epub 2019 Apr 4.
Over 43 million immigrants live in the United States (U.S.). Foreign-born populations experience multiple disparities related to human papillomavirus (HPV), including higher cervical cancer mortality rates, yet little research has examined the prevalence of genital HPV infection among this population. We used data from 1,822 women and 1,622 men ages 20-59 in the U.S. who participated in the 2013-2014 National Health and Nutrition Examination Survey (NHANES). Participants reported their nativity status (foreign- vs. U.S.-born) and provided biospecimens for HPV testing. We assessed nativity differences in the prevalence of three HPV infection outcomes (any HPV type, high-risk HPV type, and vaccine-preventable HPV type) using weighted logistic regression. Overall, 40% of women and 46% of men tested positive for any type of HPV. Compared to women born in the U.S., foreign-born women had a lower prevalence of infection with any HPV type (32% vs. 42%, .01). Compared to men born in the U.S., foreign-born men had a lower prevalence of all HPV infection outcomes (any type: 39% vs. 48%; high-risk: 22% vs. 34%; vaccine-preventable: 12% vs. 16%; all < .05). Multivariable models attenuated several of these differences, though foreign-born men had lower odds of infection with a high-risk HPV type (OR = 0.75; 95% CI: 0.60-0.93, .01) after adjusting for covariates. Although lower than among their U.S.-born counterparts, HPV infection is prevalent among foreign-born women and men in the U.S. Findings can help inform strategic communication campaigns and targeted HPV vaccination and cervical cancer screening efforts for immigrant populations.
超过 4300 万移民居住在美国（美国）。出生在外国的人群在人乳头瘤病毒（HPV）方面存在多种差异，包括更高的宫颈癌死亡率，但很少有研究检查过这一人群的生殖器 HPV 感染患病率。我们使用了美国参加 2013-2014 年全国健康和营养检查调查（NHANES）的 1822 名女性和 1622 名 20-59 岁的男性的数据。参与者报告了他们的出生地状况（外国出生与美国出生）并提供了用于 HPV 检测的生物样本。我们使用加权逻辑回归评估了 HPV 感染三种结局（任何 HPV 类型、高危 HPV 类型和疫苗可预防 HPV 类型）的出生地差异。总体而言，40%的女性和 46%的男性检测出任何 HPV 类型呈阳性。与在美国出生的女性相比，外国出生的女性 HPV 感染的总体流行率较低（32%对 42%，.01）。与在美国出生的男性相比，外国出生的男性所有 HPV 感染结局（任何类型：39%对 48%；高危：22%对 34%；疫苗可预防：12%对 16%；均 < .05）的流行率较低。虽然多变量模型削弱了这些差异中的几个，但在调整了协变量后，外国出生的男性感染高危 HPV 类型的几率较低（OR=0.75；95%CI：0.60-0.93，.01）。尽管低于其美国出生的同龄人，HPV 感染在移民人群中的外国出生的女性和男性中仍很普遍。这些发现有助于为移民人口提供战略宣传运动和有针对性的 HPV 疫苗接种和宫颈癌筛查工作。
