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[Immunologic analysis of the antigenic properties of neuraminidase from drift-variants of influenza virus B].

作者信息

Rovnova Z I, Rogacheva T A, Platonova A L, Isaeva E I

出版信息

Vopr Virusol. 1988 Nov-Dec;33(6):669-74.

PMID:3073569
Abstract

The antigenic features of neuraminidases of several drift variants of influenza B virus were studied by enzyme immunoassay using antiserum to influenza B/USSR/100/83 virus neuraminidase isolated by pronase. Studies using immunosorption and competitive solid-phase enzyme immunoassay showed the presence in the antineuraminidase serum of at least two antibody subpopulations capable to inhibiting the activity of the enzyme and interacting with neuraminidase antigenic determinants: one detecting the antigenic determinant common for B/100/83 and B/Lee/40 viruses, and the other characterizing the antigenic determinant inherent in neuraminidase of B/100/83 virus and enzymes of drift variants isolated in 1970-1986 and lacking in the enzyme of B/Lee/40 virus.

摘要

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