[不同分离时期乙型流感病毒参考毒株的生物学和抗原特性]

[Characteristics of the biological and antigenic properties of reference strains of the influenza B virus at various periods of isolation].

作者信息

Podcherniaeva R Ia, Rogacheva T A, Shchipanova M V, Rovnova Z I

出版信息

Vopr Virusol. 1986 Jan-Feb;31(1):31-5.

Abstract

The results of a comparative analysis of biological and antigenic properties of reference influenza B virus strains, B/Lee/40, B/Singapore/222/79, and B/USSR/100/83, are presented. The most marked changes were found in the antigenic properties of hemagglutinin and neuraminidase. Hemagglutinins of the strains under study were found to have both common antigens and qualitatively different strain-specific determinants. The degree of intensity of immunity to the challenge B/Singapore/222/79 Pm+ virus corresponded to the intensity of antigenic relationship in the strains under study.

摘要

本文展示了对参考乙型流感病毒株B/Lee/40、B/新加坡/222/79和B/苏联/100/83的生物学和抗原特性进行比较分析的结果。在血凝素和神经氨酸酶的抗原特性方面发现了最显著的变化。所研究毒株的血凝素既有共同抗原，也有性质不同的毒株特异性决定簇。针对攻击病毒B/新加坡/222/79 Pm+的免疫强度与所研究毒株中的抗原关系强度相对应。

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