Incretin enhancement without hyperinsulinemia: α-glucosidase inhibitors.

The α-glucosidase inhibitors are a time-tested, but under-utilized, class of oral hypoglycemic effects. Recent understanding of the importance of the incretin pathway, coupled with evidence about the incretin enhancing effects of these molecules, is covered in this editorial. The authors call for greater recognition of the beneficial effects of this class of drugs in the management of Type 2 diabetes.