Gilliland S E, Speck M L
Department of Food Science North Carolina State University, Raleigh, North Carolina 27607.
J Food Prot. 1977 Dec;40(12):820-823. doi: 10.4315/0362-028X-40.12.820.
Lactobacillus acidophilus exerted antagonistic actions on growth of Staphylococcus aureus , Salmonella typhimurium , enteropathogenic Escherichia coli , and Clostridium perfringens when grown with each in associative cultures. S. aureus and C. perfringens were more sensitive to the inhibition than were S. typhimurium and E. coli . The amount of the antagonism produced varied among strains of L. acidophilus and could not be directly related to amounts of acid produced; hydrogen peroxide produced by the lactobacilli appeared to be partially responsible for the antagonistic interaction. The inhibitory effect was produced also under anaerobic conditions in a pre-reduced medium.
嗜酸乳杆菌与金黄色葡萄球菌、鼠伤寒沙门氏菌、肠道致病性大肠杆菌和产气荚膜梭菌在混合培养时，对这些菌的生长具有拮抗作用。金黄色葡萄球菌和产气荚膜梭菌比鼠伤寒沙门氏菌和大肠杆菌对这种抑制作用更敏感。嗜酸乳杆菌不同菌株产生的拮抗量有所不同，且与产酸量没有直接关系；乳杆菌产生的过氧化氢似乎是这种拮抗相互作用的部分原因。在预还原培养基的厌氧条件下也会产生抑制作用。
