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使用人体模型对严重体温过低进行头部和躯干复温的效果

Efficacy of Head and Torso Rewarming Using a Human Model for Severe Hypothermia.

作者信息

Kulkarni Kartik, Hildahl Erik, Dutta Ramesh, Webber Sandra C, Passmore Steven, McDonald Gerren K, Giesbrecht Gordon G

机构信息

Laboratory for Exercise and Environmental Medicine, Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Canada.

Department of Emergency Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Wilderness Environ Med. 2019 Mar;30(1):35-43. doi: 10.1016/j.wem.2018.11.005. Epub 2019 Feb 6.

Abstract

INTRODUCTION

To evaluate the rewarming effectiveness of a similar amount of heat (from a charcoal heater) applied to either the head or torso in a human model for severe hypothermia in which shivering is pharmacologically inhibited in mildly hypothermic subjects.

METHODS

Six male subjects were cooled on 3 different occasions, each in 8°C water for 60 min, or to a lowest core temperature of 35°C. Shivering was inhibited by intravenous meperidine (1.5 mg·kg), administered during the last 10 min of the cold-water immersion. Subjects then exited from the cold water, were dried, and were placed in a 3-season sleeping bag for 120 min in one of the following conditions: spontaneous rewarming only, charcoal heater on the head, or charcoal heater on the torso. Supplemental meperidine (to a maximum cumulative dose of 3.3 mg·kg) was administered as required during rewarming to suppress shivering.

RESULTS

No significant differences were found in the postcooling afterdrop amount or core rewarming rates among the 3 conditions (0.8°C·h). During the last 30 min of rewarming the net heat gain was significantly higher in the head (85.8±25.3 W) and torso (81.5±6.3 W) conditions compared with the spontaneous condition (56.9±12 W) (P<0.05).

CONCLUSIONS

In our study, head and torso warming had the same core rewarming rates when shivering was pharmacologically inhibited in mildly hypothermic subjects. Therefore, in nonshivering cold subjects, head warming is a viable alternative if torso warming is contraindicated (eg, when performing cardiopulmonary resuscitation or working on open chest wounds).

摘要

引言

在一个人体模型中,对轻度低温受试者进行药物抑制颤抖后,评估将等量热量(来自炭火加热器)应用于头部或躯干对严重低温的复温效果。

方法

六名男性受试者在3个不同场合接受降温,每次在8°C水中浸泡60分钟,或降至最低核心体温35°C。在冷水浸泡的最后10分钟静脉注射哌替啶(1.5mg·kg)以抑制颤抖。然后受试者离开冷水,擦干身体,并在以下条件之一的三季睡袋中放置120分钟:仅自然复温、头部放置炭火加热器或躯干放置炭火加热器。复温期间根据需要给予补充哌替啶(最大累积剂量为3.3mg·kg)以抑制颤抖。

结果

三种条件下(0.8°C·h)的降温后体温下降量或核心复温率均无显著差异。在复温的最后30分钟内,与自然复温条件(56.9±12W)相比,头部(85.8±25.3W)和躯干(81.5±6.3W)条件下的净热量增加显著更高(P<0.05)。

结论

在我们的研究中,当对轻度低温受试者进行药物抑制颤抖时,头部和躯干升温具有相同的核心复温率。因此,在无颤抖的寒冷受试者中,如果躯干升温禁忌(例如,进行心肺复苏或处理开放性胸部伤口时),头部升温是一种可行的替代方法。

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