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单纯椎板切除术与椎板切除术加后路内固定术治疗脊髓型颈椎病的临床比较

Clinical comparison between simple laminectomy and laminectomy plus posterior instrumentation in surgical treatment of cervical myelopathy.

作者信息

Gargiulo G, Girardo M, Rava A, Coniglio A, Cinnella P, Massè A, Fusini F

机构信息

Spine Surgery Unit, Orthopaedic and Trauma Centre, Azienda Ospedaliera Città della Salute e della Scienza, Via Zuretti 29, Turin, Italy.

Department of Orthopaedic and Traumatology, Orthopaedic and Trauma Centre, Azienda Ospedaliera Città della Salute e della Scienza, University of Turin, Via Zuretti 29, Turin, Italy.

出版信息

Eur J Orthop Surg Traumatol. 2019 Jul;29(5):975-982. doi: 10.1007/s00590-019-02395-6. Epub 2019 Feb 8.

Abstract

BACKGROUND

Posterior stabilization in patients treated with laminectomy for spondylotic cervical myelopathy is still a debate. Despite both being reported in literature by several authors, some controversies still exist. The aim of this study is to compare clinical and radiological outcomes in patients treated with laminectomy or laminectomy with posterior stabilization.

MATERIAL AND METHODS

We retrospectively evaluated 42 patients affected by cervical myelopathy (mean age 70.43 ± 5.03 years), 19 treated with laminectomy (group A) and 23 with laminectomy and posterior instrumentation (group B). Neurological status was assessed with Nurick scale, pain with VAS and radiological parameters with C2-C7 SVA, T1 slope and C2-C7 lordosis, clinical function with modified Japanese Orthopaedic Association score (JOA). Also, surgery time and blood loss were recorded. Student's t test was used for continuous variables, while Kruskal-Wallis test was used for categorical values.

RESULTS

No differences were found in postoperative Nurick scale (p = 0.587), VAS (p = 0.62), mJOA (p = 0.197) and T1 slope (p = 0.559), while laminectomy with fusion showed better postoperative cervical lordosis (p = 0.007) and C2-C7 SVA (p < 0.00001), but higher blood loss (p < 0.00001) and surgical time (p < 0.00001). Both groups showed better Nurick scale (p = 0.00017 for group A and p = 0.00081 for group B), VAS (p = 0.02 for group A and p = 0.046 for group B) and mJOA (p < 0.00001 for both groups) than preoperative values.

CONCLUSIONS

Both treatments are a valuable choice, offering some benefits and disadvantages against each other. Each procedure must be carefully evaluated on the basis of patients' general status, preoperative pain, signs of instability and potential benefits from cervical alignment correction.

摘要

背景

对于接受椎板切除术治疗脊髓型颈椎病的患者,后路稳定术仍存在争议。尽管有多位作者在文献中报道了这两种方法,但仍存在一些争议。本研究的目的是比较接受单纯椎板切除术或椎板切除术后行后路稳定术患者的临床和影像学结果。

材料与方法

我们回顾性评估了42例脊髓型颈椎病患者(平均年龄70.43±5.03岁),其中19例行单纯椎板切除术(A组),23例行椎板切除术后行后路内固定术(B组)。采用Nurick量表评估神经功能状态,视觉模拟评分法(VAS)评估疼痛程度,通过C2-C7矢状面垂直轴(SVA)、T1斜率和C2-C7前凸角评估影像学参数,采用改良日本骨科协会评分(JOA)评估临床功能。此外,记录手术时间和失血量。连续变量采用Student's t检验,分类变量采用Kruskal-Wallis检验。

结果

术后Nurick量表评分(p = 0.587)、VAS评分(p = 0.62)、改良JOA评分(p = 0.197)和T1斜率(p = 0.559)两组间无差异,而融合内固定组术后颈椎前凸角(p = 0.007)和C2-C7 SVA(p < 0.00001)更好,但失血量(p < 0.00001)和手术时间(p < 0.00001)更多。两组术后Nurick量表评分(A组p = 0.00017,B组p = 0.00081)、VAS评分(A组p = 0.02,B组p = 0.046)和改良JOA评分(两组均p < 0.00001)均优于术前。

结论

两种治疗方法都是有价值的选择,各有优缺点。必须根据患者的一般状况、术前疼痛情况、不稳定体征以及颈椎对线矫正的潜在益处,对每种手术方法进行仔细评估。

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