[Lipopolysaccharide-specific antibodies in intestinal lavage fluid, bile and serum of mice after oral application of inactivated Escherichia coli].

The formation of antibodies against lipopolysaccharide in the mouse after daily administration of 10(10) killed Escherichia coli M17 (serotype 02:K1) was studied. An IgA response in gut is already established at the first day after an immunization period of 5 days. The kinetics of antibody formation in gut lavage fluid and bile are similar. In comparison lipopolysaccharide-specific IgG antibodies against lipopolysaccharide in serum are raised later.