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液压扩张对血液透析患者动静脉瘘的影响。

Effect of Hydraulic Expansion on Arteriovenous Fistula of Hemodialysis Patients.

机构信息

Department of Nephrology, Blood Purification Center, Jinan Central Hospital, Shandong University, Jinan, Shandong, People's Republic of China.

Department of Nephrology, Qianfoshan Hospital, Shandong University, Jinan, Shandong, People's Republic of China.

出版信息

Thorac Cardiovasc Surg. 2021 Jan;69(1):63-69. doi: 10.1055/s-0039-1678543. Epub 2019 Feb 9.

Abstract

BACKGROUND

Chronic kidney disease has become a serious public health problem in China. Our study is to explore effect of hydraulic expansion on arteriovenous fistula (AVF) of hemodialysis patients.

METHODS

A total of 190 patients with end-stage renal disease (ESRD) were randomly divided into hydraulic expansion group ( = 117) and conventional surgery group ( = 73). Age, sex, the cause of ESRD, height, weight, body mass index (BMI), blood pressure, and diameter of artery and vein from ultrasonography before surgery from patients were recorded. Doppler ultrasonography of vessel was performed with a 12-MHz scanning probe for vascular measurements. The time of first cannulation was recorded. Primary and secondary patency rates were compared between the two groups.

RESULTS

The mean arterial pressure for this cohort of patients was around 98.12 mm Hg. The mean diameters of artery and vein ready for anastomoses measured by ultrasonography before surgery were 1.96 and 2.04 mm, respectively. Age, weight, BMI, sex ratio, the cause of renal failure, history of catheter insertion, mean arterial pressure, frequency of hemodialysis, blood flow of hemodialysis, and the mode of anastomoses of AVF in conventional surgery group were similar to hydraulic expansion group. There were no differences in stroke volume of radius arterial and venous pressure before dilation between the two groups. The stroke volume of radius artery increased significantly after hydraulic expansion than before dilation and control group. The primary patency rates of AVF in patients with hydraulic expansion were higher significantly than conventional surgery group. The secondary patency rates in conventional surgery group were not different from hydraulic expansion group.

CONCLUSION

Hydraulic expansion showed no difference from conventional surgery in complication after operation, and could decrease the time reliance on catheters and the risk of catheter-related infection, thrombosis, and decrease the related medical care costs.

摘要

背景

慢性肾脏病已成为中国严重的公共卫生问题。本研究旨在探讨水压扩张对血液透析患者动静脉瘘(AVF)的影响。

方法

将 190 例终末期肾病(ESRD)患者随机分为水压扩张组(n=117)和常规手术组(n=73)。记录患者术前的年龄、性别、ESRD 病因、身高、体重、体重指数(BMI)、血压、超声检查的动脉和静脉直径。使用 12MHz 扫描探头进行血管多普勒超声检查,进行血管测量。记录首次穿刺时间。比较两组患者的一级和二级通畅率。

结果

该队列患者的平均动脉压约为 98.12mmHg。术前超声测量的吻合前动脉和静脉的平均直径分别为 1.96mm 和 2.04mm。常规手术组与水压扩张组的年龄、体重、BMI、性别比、肾衰竭病因、导管插入史、平均动脉压、血液透析频率、血液透析血流量和 AVF 吻合方式均相似。两组扩张前桡动脉动脉搏动量和静脉压无差异。水压扩张后桡动脉动脉搏动量明显高于扩张前和对照组。水压扩张组患者的 AVF 一级通畅率明显高于常规手术组。常规手术组的二级通畅率与水压扩张组无差异。

结论

水压扩张与术后并发症无差异,可减少对导管的时间依赖,降低导管相关感染、血栓形成的风险,并降低相关医疗费用。

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