Degnan Andrew J, Zhu Xiaowei, Flowers Colleen, Fox William W, Zhang Huayan, Saul David
Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA.
Curr Probl Diagn Radiol. 2019 May-Jun;48(3):247-250. doi: 10.1067/j.cpradiol.2018.12.005. Epub 2018 Dec 7.
Partial liquid ventilation is proposed as an alternative ventilation strategy to reduce surface tension, increase alveolar recruitment, and decrease inflammation. Studied in acute respiratory distress and other indications, liquid ventilation is being revisited for infants with bronchopulmonary dysplasia. Perfluorooctyl bromide used for liquid ventilation is radiopaque, allowing radiographic visualization of lung liquid ventilation patterns that may provide additional insight into pulmonary pathophysiology. Current protocols utilize reduced liquid dosing, resulting in unique imaging features. We discuss optimal radiographic technique and report initial ultrasound evaluation results. With renewed interest in partial liquid ventilation, it may be helpful for pediatric radiologists to familiarize themselves with the clinical use and radiographic appearance of liquid ventilation material.
部分液体通气被提议作为一种替代通气策略，以降低表面张力、增加肺泡复张并减轻炎症。在急性呼吸窘迫及其他适应症中进行了研究，目前正在重新审视液体通气在支气管肺发育不良婴儿中的应用。用于液体通气的全氟辛基溴是不透射线的，这使得可以通过放射成像观察肺液体通气模式，从而为肺部病理生理学提供更多见解。当前的方案采用减少液体剂量的方法，产生了独特的成像特征。我们讨论了最佳的放射成像技术并报告了初步的超声评估结果。随着对部分液体通气重新产生兴趣，儿科放射科医生熟悉液体通气材料的临床应用和放射成像表现可能会有所帮助。
