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本文引用的文献

1
Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months.吗啡生物转化基因和新生儿临床因素可预测极低出生体重儿 18 个月时的行为问题。
EBioMedicine. 2019 Feb;40:655-662. doi: 10.1016/j.ebiom.2019.01.042. Epub 2019 Jan 30.
2
Developmental Changes in Pharmacokinetics and Pharmacodynamics.发育过程中的药代动力学和药效学变化。
J Clin Pharmacol. 2018 Oct;58 Suppl 10:S10-S25. doi: 10.1002/jcph.1284.
3
Non-maturational covariates for dynamic systems pharmacology models in neonates, infants, and children: Filling the gaps beyond developmental pharmacology.新生儿、婴儿和儿童动态系统药理学模型的非成熟性协变量：填补发育药理学之外的空白。
Eur J Pharm Sci. 2017 Nov 15;109S:S27-S31. doi: 10.1016/j.ejps.2017.05.023. Epub 2017 May 12.
4
Smaller Cerebellar Growth and Poorer Neurodevelopmental Outcomes in Very Preterm Infants Exposed to Neonatal Morphine.暴露于新生儿期吗啡的极早产儿小脑生长较小且神经发育结局较差。
J Pediatr. 2016 May;172:81-87.e2. doi: 10.1016/j.jpeds.2015.12.024. Epub 2016 Jan 4.
5
Sedation and analgesia practices in neonatal intensive care units (EUROPAIN): results from a prospective cohort study.新生儿重症监护病房镇静和镇痛实践（EUROPAIN）：一项前瞻性队列研究的结果。
Lancet Respir Med. 2015 Oct;3(10):796-812. doi: 10.1016/S2213-2600(15)00331-8. Epub 2015 Sep 24.
6
Does neonatal morphine use affect neuropsychological outcomes at 8 to 9 years of age?新生儿使用吗啡是否会影响 8 至 9 岁时的神经心理学结局？
Pain. 2013 Mar;154(3):449-458. doi: 10.1016/j.pain.2012.12.006. Epub 2012 Dec 20.
7
Long-term effects of routine morphine infusion in mechanically ventilated neonates on children's functioning: five-year follow-up of a randomized controlled trial.机械通气新生儿常规吗啡输注对儿童功能的长期影响：一项随机对照试验的 5 年随访。
Pain. 2011 Jun;152(6):1391-1397. doi: 10.1016/j.pain.2011.02.017. Epub 2011 Mar 12.
8
Opioid analgesia in the newborn.新生儿的阿片类镇痛
Eur J Pain. 2005 Apr;9(2):105-8. doi: 10.1016/j.ejpain.2004.05.005.
9
Effects of morphine analgesia in ventilated preterm neonates: primary outcomes from the NEOPAIN randomised trial.吗啡镇痛对机械通气早产儿的影响：NEOPAIN随机试验的主要结果
Lancet. 2004 May 22;363(9422):1673-82. doi: 10.1016/S0140-6736(04)16251-X.
10
Routine morphine infusion in preterm newborns who received ventilatory support: a randomized controlled trial.接受通气支持的早产儿常规吗啡输注：一项随机对照试验。
JAMA. 2003 Nov 12;290(18):2419-27. doi: 10.1001/jama.290.18.2419.

Towards personalized medicine in preterm newborns: Morphine analgesia predicted by genotype.

作者信息

Simons Sinno H P

机构信息

Division of Neonatology, Department of Paediatrics, Erasmus UMC, Sophia Children's Hospital, Rotterdam, the Netherlands.

出版信息

EBioMedicine. 2019 Feb;40:41-42. doi: 10.1016/j.ebiom.2019.02.003. Epub 2019 Feb 7.

DOI:10.1016/j.ebiom.2019.02.003
PMID:30738831
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6413580/
Abstract
摘要