Division of Pediatric Endocrinology, Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA,
Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA,
Horm Res Paediatr. 2019;91(2):83-92. doi: 10.1159/000496354. Epub 2019 Feb 8.
Survival from childhood cancer has improved dramatically over the last few decades, resulting in an increased need to address the long-term follow-up and care of childhood cancer survivors. Appropriate linear growth is an important measure of health, with alterations of growth in children and short adult height in those who have completed growth serving as potential indicators of the sequelae of the underlying diagnosis or the cancer treatments. It is therefore critical that clinicians, particularly endocrinologists, be familiar with the patterns of altered growth which may be seen following diagnosis and treatment for childhood cancer. In this article, we will review the growth alterations seen in childhood cancer survivors, focusing on risk factors and considerations in evaluation and care.
在过去的几十年中,儿童癌症的存活率有了显著提高,因此需要更多地关注儿童癌症幸存者的长期随访和护理。适当的线性生长是健康的重要指标,儿童生长的改变和已经完成生长的成年人身高偏矮可能是潜在的疾病诊断或癌症治疗后遗症的指标。因此,临床医生,特别是内分泌学家,熟悉儿童癌症诊断和治疗后可能出现的生长改变模式至关重要。在本文中,我们将回顾儿童癌症幸存者中出现的生长改变,重点讨论评估和护理中的危险因素和注意事项。