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Precision Tuning of DNA- and Poly(ethylene glycol)-Based Nanoparticles via Coassembly for Effective Antisense Gene Regulation.

作者信息

Wang Dali, Lu Xueguang, Jia Fei, Tan Xuyu, Sun Xiaoya, Cao Xueyan, Wai Francesco, Zhang Chuan, Zhang Ke

机构信息

Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. China.

出版信息

Chem Mater. 2017 Dec 12;29(23):9882-9886. doi: 10.1021/acs.chemmater.7b03520. Epub 2017 Nov 18.

DOI:10.1021/acs.chemmater.7b03520
PMID:30739990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6366845/
Abstract
摘要

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本文引用的文献

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The chemical evolution of oligonucleotide therapies of clinical utility.具有临床应用价值的寡核苷酸疗法的化学进化
Nat Biotechnol. 2017 Mar;35(3):238-248. doi: 10.1038/nbt.3765. Epub 2017 Feb 27.
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Effect of PEG Architecture on the Hybridization Thermodynamics and Protein Accessibility of PEGylated Oligonucleotides.PEG 结构对聚乙二醇化寡核苷酸杂交热力学和蛋白质可及性的影响。
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Blurring the Role of Oligonucleotides: Spherical Nucleic Acids as a Drug Delivery Vehicle.模糊寡核苷酸的角色：作为药物递送载体的球形核酸。
J Am Chem Soc. 2016 Aug 31;138(34):10834-7. doi: 10.1021/jacs.6b07554. Epub 2016 Aug 18.
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Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes.通过非阳离子、聚乙二醇刷实现有效的反义基因调控。
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From the RNA world to the clinic.从 RNA 世界到临床。
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