通过分析牙科修复材料的氟释放曲线来比较其再矿化潜力。

A comparison of the remineralizing potential of dental restorative materials by analyzing their fluoride release profiles.

作者信息

Porenczuk Alicja, Jankiewicz Bartłomiej, Naurecka Magdalena, Bartosewicz Bartosz, Sierakowski Bartosz, Gozdowski Dariusz, Kostecki Jerzy, Nasiłowska Barbara, Mielczarek Agnieszka

机构信息

Restorative Dentistry Department, Warsaw Medical University, Poland.

Institute of Optoelectronics, Military University of Technology, Warszawa, Poland.

出版信息

Adv Clin Exp Med. 2019 Jun;28(6):815-823. doi: 10.17219/acem/94140.

DOI:10.17219/acem/94140

PMID:30740943

Abstract

BACKGROUND

The accessibility of the remineralizing ions in teeth's environment is essential for their incorporation into caries-affected dentin. Novel bioglass-reinforced materials capable of releasing fluoride, calcium and phosphates may be particularly useful in the tissue remineralization process. A novel restorative material, ACTIVA BioActive-Restorative (Pulpdent Corp., Watertown, USA), is a hydrophilic resin-modified glassionomer cement (RMGIC) enriched with bioglass particles and fortified with a patented rubberized polymer resin. Its application in restorative dentistry may be significant, promoting remineralization of carious lesions.

OBJECTIVES

The aim of the study was to compare the fluoride ion release profiles from a bioglass-reinforced RMGIC, a conventional glass-ionomer cement (GIC) and a nanohybrid restorative polymer resin.

MATERIAL AND METHODS

The quantity of fluoride ions released from ACTIVA, Ketac Molar Quick Aplicap and Tetric EvoCeram was assessed using a fluoride-specific electrode. The surface characteristics of the preand post-experimental specimens were studied using a scanning electron microscope (SEM) and confocal microscope. An X-ray powder diffraction (XRD) analysis was additionally used to examine the chemical compositions of the dental materials.

RESULTS

The greatest quantity of fluoride ions was freed from the GIC specimens (20.698-54.118 ppm), followed by the bioglass-reinforced RMGIC (from 1.236 to 15.552 ppm) and nanohybrid polymer resin (0.370-1.148 ppm). The pre-experimental specimens of the bioglass-reinforced RMGIC were porous, while the post-experimental specimens were smoother with visible micro-cracks. The XRD analysis of the bioglass particles confirmed that the material was composed mainly of fluoride (27.70 mass%), silicon (15.62 mass%), aluminum (5.91 mass%), and calcium (5.40 mass%).

CONCLUSIONS

The fluoride ion release profile of ACTIVA was lower than the GIC Keta Molar Quick Aplicap, but significantly higher than the nanohybrid restorative polymer resin Tetric EvoCeram.

摘要

背景

牙齿环境中再矿化离子的可及性对于它们融入受龋损的牙本质至关重要。能够释放氟、钙和磷酸盐的新型生物玻璃增强材料在组织再矿化过程中可能特别有用。一种新型修复材料，ACTIVA生物活性修复材料（美国沃特敦Pulpdent公司），是一种富含生物玻璃颗粒并用专利橡胶化聚合物树脂强化的亲水性树脂改性玻璃离子水门汀（RMGIC）。其在修复牙科中的应用可能意义重大，可促进龋损病变的再矿化。

目的

本研究的目的是比较生物玻璃增强RMGIC、传统玻璃离子水门汀（GIC）和纳米混合修复聚合物树脂的氟离子释放曲线。

材料与方法

使用氟特异性电极评估从ACTIVA、Ketac Molar Quick Aplicap和Tetric EvoCeram释放的氟离子量。使用扫描电子显微镜（SEM）和共聚焦显微镜研究实验前后标本的表面特征。另外使用X射线粉末衍射（XRD）分析来检查牙科材料的化学成分。

结果

GIC标本释放的氟离子量最大（20.698 - 54.118 ppm），其次是生物玻璃增强RMGIC（1.236至15.552 ppm）和纳米混合聚合物树脂（0.370 - 1.148 ppm）。生物玻璃增强RMGIC的实验前标本是多孔的，而实验后标本更光滑，有可见的微裂纹。生物玻璃颗粒的XRD分析证实该材料主要由氟（27.70质量%）、硅（15.62质量%）、铝（5.91质量%）和钙（5.40质量%）组成。