Heuts S, Olsthoorn J R, Hermans S M M, Streukens S A F, Vainer J, Cheriex E C, Segers P, Maessen J G, Sardari Nia P
Department of Cardiothoracic Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.
Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
Neth Heart J. 2019 Apr;27(4):176-184. doi: 10.1007/s12471-019-1238-1.
Although decision-making using the heart-team approach is apparently intuitive and has a class I recommendation in most recent guidelines, supportive data is still lacking. The current study aims to demonstrate the individualised clinical pathway for mitral valve disease patients and to evaluate the outcome of all patients referred to the dedicated mitral valve heart team.
All patients who were evaluated for mitral valve pathology with or without concomitant cardiac disease between 1 January 2016 and 31 December 2016 were prospectively followed and included. Patients were evaluated, and a treatment strategy was determined by the dedicated mitral valve heart team.
One hundred and fifty-eight patients were included; 67 patients were treated surgically (isolated and concomitant surgery), 20 by transcatheter interventions and 71 conservatively. Surgically treated patients had a higher 30-day mortality rate (4.4%), which decreased when specified to a dedicated surgeon (1.7%) and in primary, elective cases (0%). This was also observed for major adverse events within 30 days. Residual mitral regurgitation >grade 2 was more frequent in the catheter-based intervention group (23.5%) compared to the surgical group (4.8%).
In conclusion, the implementation of a multidisciplinary heart team for mitral valve disease is a valuable approach for the selection of patients for different treatment modalities. Our research group will focus on a future comparative study using historical cohorts to prove the potential superiority of the dedicated multidisciplinary heart-team approach.
尽管采用心脏团队方法进行决策显然直观,且在最新指南中获得I类推荐,但仍缺乏支持性数据。本研究旨在展示二尖瓣疾病患者的个体化临床路径,并评估所有转诊至专门二尖瓣心脏团队的患者的治疗结果。
前瞻性随访并纳入2016年1月1日至2016年12月31日期间因二尖瓣病变接受评估的所有患者,无论是否伴有心脏病。由专门的二尖瓣心脏团队对患者进行评估并确定治疗策略。
共纳入158例患者;67例接受手术治疗(单纯手术和联合手术),20例接受经导管介入治疗,71例接受保守治疗。接受手术治疗的患者30天死亡率较高(4.4%),指定由专科外科医生手术时死亡率降低(1.7%),在原发性择期病例中死亡率为0%。30天内的主要不良事件也有类似情况。与手术组(4.8%)相比,基于导管介入治疗组残余二尖瓣反流>2级更为常见(23.5%)。
总之,为二尖瓣疾病实施多学科心脏团队是选择不同治疗方式患者的一种有价值的方法。我们的研究小组将专注于未来使用历史队列进行的比较研究,以证明专门的多学科心脏团队方法的潜在优势。