Suppr超能文献

重度原发性二尖瓣反流患者多学科评估转诊不足的发生率

Incidence of Underreferral to Multidisciplinary Evaluation in Severe Primary Mitral Regurgitation.

作者信息

Waldron Christina, Krane Markus, Hosoba Soh, Geirsson Arnar, Mori Makoto

机构信息

Division of Cardiac Surgery, Yale School of Medicine, New Haven, Connecticut.

Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, Technical University of Munich, Munich, Germany.

出版信息

Ann Thorac Surg Short Rep. 2023 Nov 30;2(2):241-245. doi: 10.1016/j.atssr.2023.11.015. eCollection 2024 Jun.

Abstract

BACKGROUND

Severe primary mitral regurgitation (MR) warrants multidisciplinary evaluation involving cardiac surgeons and structural interventional cardiologists. The incidence and potential impact on outcomes of missed evaluation remain unknown.

METHODS

We conducted a retrospective cohort study of patients with new diagnoses of severe primary MR from an echocardiography database within a large health care network. Of 37,749 unique patients with echocardiograms, 126 had severe primary MR. We compared the 2-year survival of patients who did and did not undergo multidisciplinary evaluation. Propensity score matching was performed on the basis of The Society of Thoracic Surgeons Predicted Risk of Mortality for mitral repair.

RESULTS

Of 126 patients with severe primary MR (median age, 79 years [interquartile range, 68-89 years]; 60% women), 37 (29%) underwent multidisciplinary evaluation. Evaluated patients were younger (71 [58-79] years vs 84 [73-90] years), and of those, 26 (70%) underwent operations within 37 days of evaluation. The Society of Thoracic Surgeons Predicted Risk of Mortality median was 1% (1%-5%) and 4% (1%-10%) for evaluated and unevaluated patients, respectively. Of the 74 patients matched, the mortality rate was lower in evaluated patients at 90 days (11% [n = 4] vs 27% [n = 10];  = .08) and 2 years (16% [n = 6] vs 35% [n = 13];  = .06).

CONCLUSIONS

The multidisciplinary referral rate for newly identified severe primary MR was low at 29%, with underreferral of low-risk, potentially operative candidates. The observed improved survival with multidisciplinary evaluation calls for efforts to maximize referral of this group of patients.

摘要

背景

重度原发性二尖瓣反流(MR)需要心脏外科医生和结构性介入心脏病专家进行多学科评估。漏诊评估的发生率及其对预后的潜在影响尚不清楚。

方法

我们对一个大型医疗网络中超声心动图数据库中新诊断为重度原发性MR的患者进行了一项回顾性队列研究。在37749例有超声心动图检查的患者中,126例患有重度原发性MR。我们比较了接受和未接受多学科评估的患者的2年生存率。根据胸外科医师协会二尖瓣修复预测死亡风险进行倾向评分匹配。

结果

126例重度原发性MR患者(中位年龄79岁[四分位间距68 - 89岁];60%为女性)中,37例(29%)接受了多学科评估。接受评估的患者较年轻(71[58 - 79]岁 vs 84[73 - 90]岁),其中26例(70%)在评估后37天内接受了手术。胸外科医师协会预测死亡风险中位数在接受评估和未接受评估的患者中分别为1%(1% - 5%)和4%(1% - 10%)。在74例匹配患者中,接受评估的患者在90天时的死亡率较低(11%[n = 4] vs 27%[n = 10];P = .08),2年时也是如此(16%[n = 6] vs 35%[n = 13];P = .06)。

结论

新确诊的重度原发性MR的多学科转诊率较低,为29%,低风险、可能适合手术的患者转诊不足。多学科评估观察到的生存率提高,需要努力使这类患者的转诊最大化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db18/11708365/ef629d8118a6/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验