Pediatric Neurology and Neurorehabilitation Unit, Department of Pediatrics, University Hospital of Lausanne, Lausanne, Switzerland.
Pediatric Neurology and Neurorehabilitation Unit, Department of Pediatrics, University Hospital of Lausanne, Lausanne, Switzerland.
Sleep Med. 2019 Mar;55:26-32. doi: 10.1016/j.sleep.2018.11.016. Epub 2018 Dec 14.
Children with motor disabilities such as cerebral palsy or neuromuscular diseases present more sleep disorders than their typically developing (TD) peers. However, research on these populations has always been performed using historical normative datasets or controls such as siblings. Therefore, we assessed the sleep quality of children with motor disabilities in comparison with a large, contemporary, general population sample.
Demographic, medical, and the Sleep Disturbance Scale for Children (SDSC) questionnaires were sent to parents of children aged 4-18 years and followed by our tertiary pediatric neurorehabilitation clinic, and to those of school-aged children in regional primary and secondary schools. TD participant data allowed us to set pathological sleep score thresholds (T score ≥70).
We collected 245 responses for children with motor disabilities and 2891 for those from the general population (37% and 26% response rates, respectively). Cerebral palsy was the most frequent diagnosis (N = 109, 44.5%). Children with motor disabilities had significantly more frequent pathological sleep reported in their total SDSC score (7% vs 1.9%, odds ratio (OR) 3.98, 95% confidence interval (CI) 2.17-7.27, p < 0.001) and in five subscores. Single-parent households and drug-resistant epilepsy showed significant positive associations with pathological sleep among children with motor disabilities. For TD peers, parental unemployment and parental nationality were positively associated with pathological sleep.
This population-based study robustly estimated the prevalence of sleep disorders in children with motor disabilities. Sleep disorders were significantly more frequent in children with motor disabilities, but at a lower frequency than previously reported.
脑瘫或神经肌肉疾病等运动障碍儿童比其典型发育（TD）同龄人更容易出现睡眠障碍。然而，这些人群的研究一直使用历史标准数据集或兄弟姐妹等对照进行。因此，我们评估了运动障碍儿童的睡眠质量，并与大型当代一般人群样本进行了比较。
向 4-18 岁儿童的家长以及我们的三级儿科神经康复诊所发送了人口统计学、医学和儿童睡眠障碍量表（SDSC）问卷，并向学区的中小学生家长发送了问卷。TD 参与者的数据使我们能够设定病理性睡眠评分阈值（T 评分≥70）。
我们共收集了 245 名运动障碍儿童和 2891 名普通人群儿童的反应（分别为 37%和 26%的反应率）。脑瘫是最常见的诊断（N=109，44.5%）。运动障碍儿童的 SDSC 总分和五个亚量表的病理性睡眠报告频率明显更高（7%对 1.9%，优势比（OR）3.98，95%置信区间（CI）2.17-7.27，p<0.001）。单亲家庭和耐药性癫痫与运动障碍儿童的病理性睡眠呈显著正相关。对于 TD 同龄人，父母失业和父母国籍与病理性睡眠呈正相关。
这项基于人群的研究可靠地估计了运动障碍儿童睡眠障碍的患病率。运动障碍儿童的睡眠障碍明显更频繁，但频率低于之前的报告。
