Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Cardiovascular Research Centre, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Nutrients. 2019 Feb 8;11(2):357. doi: 10.3390/nu11020357.
Type-2 diabetes (T2D) is one of the major global health challenges and a substantial economic burden. Egg and egg-derived components have been indicated to possess antioxidant, anti-inflammatory, anti-hypertensive, immunomodulatory, and anti-cancer activities. However, the scientific evidence about the benefits of egg on T2D is debatable. The relationship between egg consumption and the risk of T2D from observational epidemiological studies is not consistent. Interventional clinical studies, however, provide promising evidence that egg consumption ameliorates the risk of T2D. Current research progress also indicates that some egg components and egg-derived peptides might be beneficial in the context of T2D, in terms of insulin secretion and sensitivity, oxidative stress, and inflammation, suggesting possible application on T2D management. The current review summarizes recent clinical investigations related to the influence of egg consumption on T2D risk and in vivo and in vitro studies on the effect and mechanism of egg components and egg-derived peptides on T2D.
2 型糖尿病（T2D）是全球主要的健康挑战之一，也是一个巨大的经济负担。鸡蛋及其衍生成分具有抗氧化、抗炎、抗高血压、免疫调节和抗癌作用。然而，关于鸡蛋对 T2D 的益处的科学证据尚存在争议。来自观察性流行病学研究的鸡蛋摄入与 T2D 风险之间的关系并不一致。然而，干预性临床研究提供了有希望的证据，表明鸡蛋摄入可以降低 T2D 的风险。目前的研究进展还表明，一些鸡蛋成分和鸡蛋衍生肽在 T2D 方面可能是有益的，包括胰岛素分泌和敏感性、氧化应激和炎症，这表明它们可能在 T2D 的管理中有潜在的应用。本综述总结了最近与鸡蛋摄入对 T2D 风险的影响相关的临床研究，以及关于鸡蛋成分和鸡蛋衍生肽对 T2D 的作用和机制的体内和体外研究。
