Saeed Waseem Sharaf, Al-Odayni Abdel-Basit, Alrahlah Ali, Alghamdi Abdulaziz Ali, Aouak Taieb
Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Restorative Dental Sciences Department, Engineer Abdullah Bugshan research chair for Dental and Oral Rehabilitation College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.
Materials (Basel). 2019 Feb 10;12(3):528. doi: 10.3390/ma12030528.
Titanium dioxide/poly(δ-valerolactone) (TiO₂/Pδ-VL) nanohybrid material containing interconnected pores with sizes in the range 80⁻150 μm were prepared by the solvent casting and polymer melting routes, and the dispersion of the TiO₂ nanofiller in the Pδ-VL matrix and its adhesion were characterized by X-ray diffraction, differential scanning calorimetry, and scanning electron microscopy. A significant depression in the glass transition temperature () and melting temperature ( values were revealed for the polymer nanocomposites prepared by the solvent casting technique. For the potential application of the prepared materials in the biomedical domain, complementary analyses were performed to examine the dynamic mechanical properties, and cell adhesion (using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay), and the results obtained for the samples prepared by the two methods were compared. Interconnected pores were successively produced in the new material by employing naphthalene microparticles as a porogen for the first time, and the results obtained were very promising.
通过溶剂浇铸和聚合物熔融法制备了具有尺寸范围为80⁻150μm的相互连通孔隙的二氧化钛/聚（δ-戊内酯）（TiO₂/Pδ-VL）纳米杂化材料，并用X射线衍射、差示扫描量热法和扫描电子显微镜对TiO₂纳米填料在Pδ-VL基体中的分散及其粘附性进行了表征。对于通过溶剂浇铸技术制备的聚合物纳米复合材料，其玻璃化转变温度（）和熔点（值）出现了显著降低。为了将所制备的材料潜在应用于生物医学领域，进行了补充分析以研究动态力学性能和细胞粘附（使用3-（4,5-二甲基噻唑-2-基）-2,5-二苯基四氮唑溴盐（MTT）测定法），并比较了通过两种方法制备的样品所获得的结果。首次使用萘微粒作为致孔剂在新材料中连续产生了相互连通的孔隙，所获得的结果非常有前景。
