Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Product Quality and Safety, Ministry of Agriculture, Beijing, 100081, P. R. China.
Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, 12211 Giza, Egypt 3.
J Nanosci Nanotechnol. 2019 Jun 1;19(6):3310-3318. doi: 10.1166/jnn.2019.16138.
A magnetic zeolitic imidazolate framework nanohybrid (Fe₃O₄/ZIF-8) was synthesized and applied as an efficient magnetic solid-phase extraction (MSPE) adsorbent for fast adsorption and separation of clothianidin, imidacloprid, acetamiprid, and thiacloprid from various water samples. Fe₃O₄ and ZIF-8 were combined via a simple modified method and the obtained nanohybrid (Fe₃O₄/ZIF-8) showed both excellent adsorption capacity and convenient magnetic property. ZIF-8 was found to play a dominant role in adsorbing the analytes and π-π interaction was found to be the main adsorption mechanism of analytes by Fe₃O₄/ZIF-8. Parameters affecting the MSPE efficiency, such as the Fe₃O₄ amount loaded onto the ZIF-8, salt and pH of the sample solution, extraction time, and the type and volume of desorption solvent, were systematically evaluated. Under the optimum conditions, the developed MSPE coupled with LC-MS/MS achieved good linearities (R² > 0.9940) in the range of 10-800 μg L with low limits of detection (0.03-0.3 μg L) and satisfactory recoveries of 79.5-108.2% with relative standard deviations (RSDs) <10%. The method was successfully applied to monitor various water samples and conclusively highlighted the excellent flexibility and practicability of Fe₃O₄/ZIF-8 for analyzing emerging environmental contaminants in various types of water samples.
一种磁性沸石咪唑酯骨架纳米复合材料（Fe3O4/ZIF-8）被合成并用作高效的磁固相萃取（MSPE）吸附剂，用于从各种水样中快速吸附和分离噻虫啉、吡虫啉、噻虫胺和噻虫嗪。Fe3O4 和 ZIF-8 通过一种简单的改良方法结合在一起，所得到的纳米复合材料（Fe3O4/ZIF-8）表现出优异的吸附能力和方便的磁性。研究发现，ZIF-8 对分析物的吸附起主导作用，而 Fe3O4/ZIF-8 对分析物的主要吸附机制是π-π相互作用。系统地评估了影响 MSPE 效率的参数，如负载在 ZIF-8 上的 Fe3O4 量、样品溶液的盐度和 pH 值、萃取时间以及解吸溶剂的类型和体积。在最佳条件下，开发的 MSPE 与 LC-MS/MS 相结合，在 10-800 μg L 的范围内实现了良好的线性（R²>0.9940），检出限低（0.03-0.3 μg L），回收率为 79.5-108.2%，相对标准偏差（RSD）<10%。该方法成功应用于监测各种水样，并最终突出了 Fe3O4/ZIF-8 分析各种类型水样中新兴环境污染物的优异灵活性和实用性。
