Gelre Hospitals Apeldoorn, Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands.
Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands.
J Crit Care. 2019 Jun;51:51-56. doi: 10.1016/j.jcrc.2019.01.027. Epub 2019 Jan 29.
We hypothesized that item response based assessment of physical reserve preceding ICU admission is a predictor of survival.
We evaluated physical functioning using the Academic Medical Center Linear Disability Score (ALDS) and quality of life using the first question (SF-1) and the physical component score (PCS-12) from the Short-form 12 (SF-12) before admission by patients or by close proxies within 72 h after ICU admission during 1 year.
We developed four logistic regression models to predict 1 year mortality using the predictors age, gender, ALDS, SF-1, PCS-12. A total of 510 patients participated. Twelve months after ICU discharge, 110 patients (22%) had died. Pre-admission ALDS (p = .004), and SF-1 (p = .012) improved the prediction models with age and gender PCS-12 showed no association with mortality (p = .062). Adding the ALDS (p = .049) and the SF-1 (p = .048) to a model with age, gender and the APACHE II score (improved the model. Adding PCS-12 showed no association with mortality (p = .355).
Physical reserve as assessed by ALDS and perceived general health, preceding ICU admission is predictive of mortality. Obtaining patient's physical reserve or pre-existing perceived general health should be part of routine assessment whether a patient may benefit from ICU admission.
我们假设在 ICU 入院前对身体储备进行基于项目的评估是生存的预测指标。
我们在 ICU 入院后 72 小时内通过患者或其近亲属评估入院前的身体功能(使用学术医疗中心线性残疾评分 [ALDS])和生活质量(使用 SF-12 的第一个问题和物理成分评分 [PCS-12])。
我们开发了四个逻辑回归模型,使用年龄、性别、ALDS、SF-1、PCS-12 等预测因素预测 1 年死亡率。共有 510 名患者参与。在 ICU 出院后 12 个月,有 110 名患者(22%)死亡。入院前 ALDS(p=0.004)和 SF-1(p=0.012)改善了预测模型,而年龄和性别 PCS-12 与死亡率无关联(p=0.062)。将 ALDS(p=0.049)和 SF-1(p=0.048)添加到包含年龄、性别和 APACHE II 评分的模型中(改善了模型)。添加 PCS-12 与死亡率无关联(p=0.355)。
在 ICU 入院前评估的身体储备(通过 ALDS 和感知的总体健康状况来评估)是死亡率的预测指标。在考虑患者是否可能从 ICU 入院中受益时,应获取患者的身体储备或预先存在的总体健康感知。