Ngoc Diep Le, Vu Ly Nguyen Thi, Bich Na Pham Thi, Van Tro Chau, Minh Vinh Ngo, Trong Hao Nguyen, Van Thuong Nguyen, Hau Khang Tran, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
Medical University of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Department of Dermatology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
Open Access Maced J Med Sci. 2019 Jan 27;7(2):181-183. doi: 10.3889/oamjms.2019.067. eCollection 2019 Jan 30.
Infected eczema is one of the most common complications of eczema. The progression and treatment of infected eczema have become more complex and difficulty due to the antibiotic resistance of bacteria and the abuse of antibiotics in treatment.
Our research was conducted with the aim of investigating the severity of in vitro antibiotic resistance in patients with bacterially infected eczema at Ho Chi Minh City Hospital of Dermatology.
We studied 40 cases of patients, suffering from atopic dermatitis, contact dermatitis, vesicular palmoplantar eczema, with positive results of infected eczema.
accounted for 82.5%, followed by (15%), (12.5%), (5%) accounted for a small percentage. (2.5%) and (2.5%) accounted for the lowest percentage. Both MSSA and MRSA were completely resistant to penicillin. MRSA is completely resistant to penicillin, erythromycin, and cefuroxime, highly resistant to clindamycin (82.35%). Our research showed that was not resistant to a variety of antibiotics. It was completely resistant to tetracycline, trimethoprim/sulfamethoxazole (100%). Most bacteria are highly sensitive to linezolid, vancomycin as other studies in the world shown. There are also rifampicins, pristinamycin. Hence, it`s prioritised to be used for only patients with eczema infected with multidrug-resistant bacteria.
Penicillin is not recommended for the treatment for infected eczema. Linezolid, vancomycin has a high sensitivity to bacteria including multidrug-resistant bacteria like MRSA.
感染性湿疹是湿疹最常见的并发症之一。由于细菌的抗生素耐药性以及治疗中抗生素的滥用，感染性湿疹的进展和治疗变得更加复杂和困难。
我们的研究旨在调查胡志明市皮肤病医院细菌性感染湿疹患者的体外抗生素耐药严重程度。
我们研究了40例患有特应性皮炎、接触性皮炎、水疱性掌跖湿疹且感染性湿疹检测结果呈阳性的患者。
[此处原文似乎缺失部分具体内容]占82.5%，其次是[此处原文似乎缺失部分具体内容]（15%），[此处原文似乎缺失部分具体内容]（12.5%），[此处原文似乎缺失部分具体内容]（5%）占比小。[此处原文似乎缺失部分具体内容]（2.5%）和[此处原文似乎缺失部分具体内容]（2.5%）占比最低。甲氧西林敏感金黄色葡萄球菌（MSSA）和耐甲氧西林金黄色葡萄球菌（MRSA）对青霉素均完全耐药。MRSA对青霉素、红霉素和头孢呋辛完全耐药，对克林霉素高度耐药（82.35%）。我们的研究表明[此处原文似乎缺失部分具体内容]对多种抗生素不耐药。它对四环素、甲氧苄啶/磺胺甲恶唑完全耐药（100%）。如世界上其他研究所示，大多数细菌对利奈唑胺、万古霉素高度敏感。还有利福平、 pristinamycin。因此，仅优先用于感染多重耐药菌的湿疹患者。
不推荐使用青霉素治疗感染性湿疹。利奈唑胺、万古霉素对包括MRSA等多重耐药菌在内的细菌具有高敏感性。
