Trong Hao Nguyen, Phuong Thao Vu Thi, Van Thuong Nguyen, Thai Ha Vu, Huu Nghi Dinh, Nguyet Minh Vu, Hau Khang Tran, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
HCMC Hospital of Dermato-Venereology, Ho Chi Minh City, Vietnam.
Departments of Dermatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Open Access Maced J Med Sci. 2019 Jan 26;7(2):234-236. doi: 10.3889/oamjms.2019.059. eCollection 2019 Jan 30.
Aging is an increasing concern of modern society, particularly facial ageing. In recent years, the microinjection technique has increasingly been emphasised as a skin rejuvenation strategy. Hyaluronic acid (HA) plays an important role in the hydration of the extracellular space and can thus improve skin hydration, firmness and viscoelastic properties.
To evaluate the efficacy and safety of HA microinjection in skin rejuvenation.
We enrolled thirty participants underwent three sessions of HA microinjection involving multiple injections in the face or back of the hands at 2-week intervals. The aesthetic outcomes were assessed at baseline and after 2, 4 and 8 weeks. Clinical evaluation was based on the Global Aesthetic Improvement Scale (GAIS) and the Wrinkle Severity Rating Scale (WSRS).
Evaluation of photographs from 2, 4 and 8 weeks revealed significant clinical improvement in the brightness, texture and wrinkling of the skin. Analysis of the GAIS and WSRS scores revealed statistically significant results after 2 months.
Most of the participants felt satisfied with the treatment (93.3%).
衰老日益成为现代社会关注的焦点，尤其是面部衰老。近年来，微注射技术越来越被视为一种皮肤年轻化策略。透明质酸（HA）在细胞外空间的水合作用中发挥着重要作用，因此可以改善皮肤的水合作用、紧致度和粘弹性。
评估透明质酸微注射在皮肤年轻化中的疗效和安全性。
我们招募了30名参与者，每2周进行一次共3次透明质酸微注射，注射部位为面部或手背，进行多次注射。在基线以及2周、4周和8周后评估美学效果。临床评估基于全球美学改善量表（GAIS）和皱纹严重程度评分量表（WSRS）。
对2周、4周和8周的照片评估显示，皮肤的亮度、质地和皱纹有显著的临床改善。对GAIS和WSRS评分的分析显示，2个月后有统计学意义的结果。
大多数参与者对治疗感到满意（93.3%）。
