越南患者中HLA - B27、HLA - Cw06、HLA - DR7与银屑病关节炎的关系：疾病进展与治疗负担
The Relationship between HLA-B27, HLA-Cw06, HLA-DR7 and Psoriatic Arthritis in Vietnamese Patients: Disease Progression and Therapeutic Burden.
作者信息
Minh Vinh Ngo, Thi Van Bui, Van Tro Chau, Ngoc Trai Nguyen, Ngoc Anh Tran, Van Em Dang, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
机构信息
Pham Ngoc Thach University of Medicine, HCMC, Vietnam.
Military Central Hospital, Hanoi City, Vietnam.
出版信息
Open Access Maced J Med Sci. 2019 Jan 27;7(2):300-301. doi: 10.3889/oamjms.2019.064. eCollection 2019 Jan 30.
We conducted a prospective, cross-sectional study at Ho Chi Minh City Hospital of Dermato Venereology from January 2016 to March 2017 in 40 psoriatic arthritis (PsA) patients to evaluate the disease progression and therapeutic burden about the HLA patterns. Based upon our results, PsA with HLA-B27 (+) had a threat of severe arthritis. PsA with HLA-Cw06 (+) had a higher risk of earlier onset and shorter duration for plaque psoriasis to transform into PsA. HLA-DR7 (+) in PsA delayed the time for conversion from plaque psoriasis into PsA. These findings are quite similar to other studies in the literature.
2016年1月至2017年3月，我们在胡志明市皮肤病与性病医院对40例银屑病关节炎（PsA）患者进行了一项前瞻性横断面研究，以评估疾病进展和HLA模式的治疗负担。根据我们的结果，HLA - B27（+）的PsA有严重关节炎的风险。HLA - Cw06（+）的PsA有更高的风险，即斑块状银屑病更早发病且转化为PsA的病程更短。PsA中的HLA - DR7（+）会延迟斑块状银屑病转化为PsA的时间。这些发现与文献中的其他研究非常相似。
Zotero 插件