Parakh Keyura, Shetty Raghavendra Manjunath
Chin J Dent Res. 2019;22(1):57-64. doi: 10.3290/j.cjdr.a41776.
To evaluate and compare the efficacy of gentamicin, amoxicillin and metronidazole (GAM) antibiotic paste in noninstrumentation and instrumentation techniques in infected primary molars.
Sixty primary molars in children of 4 to 8 years were selected and divided into four groups: teeth without any periapical or furcation involvement undergoing pulpectomy by noninstrumentation (Group N1) and instrumentation (Group N2) technique using GAM antibiotic paste; teeth with periapical or furcation involvement undergoing pulpectomy by noninstrumentation (Group R1) and instrumentation (Group R2) technique using GAM antibiotic paste. Regular follow-up at 3, 6 and 12 months was carried out for each group and all the clinical and radiographic changes were evaluated statistically using SPSS software. The level of significance was set to P < 0.05.
Overall, 73.3% of success was observed in Group N1, 71.4% in Group N2, 86.7% in both Group R1 and Group R2 (P = 0.003).
The GAM lesion sterilisation and tissue repair (GAM-LSTR) technique can be an alternative to conventional pulpectomy.
评估和比较庆大霉素、阿莫西林和甲硝唑（GAM）抗生素糊剂在非器械法和器械法治疗感染乳磨牙中的疗效。
选取60颗4至8岁儿童的乳磨牙，分为四组：无根尖或根分叉病变的牙齿，采用非器械法（N1组）和器械法（N2组）使用GAM抗生素糊剂进行牙髓摘除术；有根尖或根分叉病变的牙齿，采用非器械法（R1组）和器械法（R2组）使用GAM抗生素糊剂进行牙髓摘除术。对每组进行3、6和12个月的定期随访，并使用SPSS软件对所有临床和影像学变化进行统计学评估。显著性水平设定为P < 0.05。
总体而言，N1组成功率为73.3%，N2组为71.4%，R1组和R2组均为86.7%（P = 0.003）。
GAM病变消毒和组织修复（GAM-LSTR）技术可作为传统牙髓摘除术的替代方法。
