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小儿光泽苔藓:单中心经验

Pediatric lichen nitidus: A single-center experience.

作者信息

Kundak Selcen, Çakır Yasemin

机构信息

Department of Dermatology, Dr. Behcet Uz Children's Research and Training Hospital, Izmir, Turkey.

Department of Pathology, Dr. Behcet Uz Children's Research and Training Hospital, Izmir, Turkey.

出版信息

Pediatr Dermatol. 2019 Mar;36(2):189-192. doi: 10.1111/pde.13749. Epub 2019 Feb 11.

Abstract

OBJECTIVE

Lichen nitidus (LN) is an uncommon inflammatory skin eruption. The present study aims to describe a case series of children with LN seen at a tertiary-care health center.

METHODS

Retrospective study of 17 children with biopsy-proven LN between January 2007 and March 2017. Data related with epidemiologic, clinical, and histopathologic characteristics were recorded.

RESULTS

The mean age for the onset of LN was 9 years (range: 5-17 years), and the mean duration of the skin lesions was 13 months (range: 1-48 months). Fifteen were boys (88.2%). Seven children had a generalized form of LN (41.1%) and of these, two children had severe pruritus (11.8%). Seven children had a history of co-morbid skin conditions (41.1%), including lichen planus in one patient (5.9%), lichen striatus in one patient (5.9%), psoriasis and longitudinal ridges in the nails in one patient (5.9%), and cutaneous features of atopic skin in four patients (23.5%). All of the reviewed patients had lymphohistiocytic infiltration in the dermis and basal vacuolar degeneration. Multinucleated giant cells were present in 11 (64.7%).

CONCLUSION

This case series found LN in a generalized form as well as other concurrent dermatologic conditions in nearly half of those reported. The boy predominance was also noteworthy.

摘要

目的

光泽苔藓(LN)是一种罕见的炎症性皮疹。本研究旨在描述在一家三级医疗保健中心就诊的儿童LN病例系列。

方法

对2007年1月至2017年3月期间17例经活检证实为LN的儿童进行回顾性研究。记录与流行病学、临床和组织病理学特征相关的数据。

结果

LN发病的平均年龄为9岁(范围:5 - 17岁),皮肤病变的平均持续时间为13个月(范围:1 - 48个月)。15例为男性(88.2%)。7例儿童为泛发型LN(41.1%),其中2例有严重瘙痒(11.8%)。7例儿童有合并皮肤疾病史(41.1%),包括1例扁平苔藓(5.9%)、1例线状苔藓(5.9%)、1例银屑病伴指甲纵嵴(5.9%)以及4例特应性皮炎皮肤表现(23.5%)。所有纳入研究的患者真皮均有淋巴细胞组织细胞浸润和的基底细胞空泡变性。11例的出现多核巨的细胞(64.7%)。

结论

该病例系列发现近半数报道病例的LN为泛发型,且存在其他并发皮肤病。男性的优势地位的的也的值得的注意的。

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