功能性运动障碍的神经影像学。
Neuroimaging in Functional Movement Disorders.
机构信息
Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
Neuroscience Research Centre, Institute of Molecular and Clinical Sciences, St George's University of London;, Cranmer Terrace, London, SW17 0QT, UK.
出版信息
Curr Neurol Neurosci Rep. 2019 Feb 12;19(3):12. doi: 10.1007/s11910-019-0926-y.
PURPOSE OF REVIEW
Functional movement disorders are common and disabling causes of abnormal movement control. Here, we review the current state of the evidence on the use of neuroimaging in Functional movement disorders, particularly its role in helping to unravel the pathophysiology of this enigmatic condition.
RECENT FINDINGS
In recent years, there has been a shift in thinking about functional movement disorder, away from a focus on high-level psychological precipitants as in Freudian conversion theories, or even an implicit belief they are 'put-on' for secondary gain. New research has emphasised novel neurobiological models incorporating emotional processing, self-representation and agency. Neuroimaging has provided new insights into functional movement disorders, supporting emerging neurobiological theories implicating dysfunctional emotional processing, self-image and sense of agency. Recent studies have also found subtle structural brain changes in patients with functional disorders, arguing against a strict functional/structural dichotomy.
目的综述
功能性运动障碍是一种常见且具致残性的运动控制异常病因。在此，我们对神经影像学在功能性运动障碍中的应用的现有证据进行综述，尤其探讨了其在帮助阐明这一复杂病症病理生理学中的作用。
最近发现
近年来，对功能性运动障碍的认识发生了转变，不再关注弗洛伊德转换理论中所强调的高级心理诱发因素，甚至也不再认为它们是为了获得次要利益而“装出来的”。新的研究强调了包含情绪处理、自我表现和自主性的新神经生物学模型。神经影像学为功能性运动障碍提供了新的见解，支持了新兴的神经生物学理论，即涉及功能失调的情绪处理、自我形象和自主性。最近的研究还发现功能性障碍患者存在细微的结构性脑改变，这反对了严格的功能性/结构性二分法。
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