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Possible involvement of nuclei in cadmium-induced modifications of cultured cells.

作者信息

Fighetti M A, Miele M, Montella A, Desole M S, Congiu A M, Anania V

机构信息

Institutes of Pharmacology, University of Sassari, Italy.

出版信息

Arch Toxicol. 1988;62(6):476-8. doi: 10.1007/BF00288354.

Abstract

Reduced metaphase number and shortening of metaphase chromosomes were detected in McCoy cells exposed to 100 microM CdSO4 (maximal exposure time: 7 h). One hour exposure to 109Cd was enough to label the cell nucleus. This possibly suggests an early nuclear involvement in Cd-induced cell damage.

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