Krbková Lenka, Kybicová Kateřina, Pícha Dušan, Roháčová Hana, Smíšková Dita
Department of Children's Infectious Diseases, Faculty of Medicine and University Hospital, Masaryk University, Brno, Czech Republic, e-mail:
Klin Mikrobiol Infekc Lek. 2018 Sep;24(3):88-99.
The national guideline aims to highlight the latest knowledge about clinical manifestations of the infection, to summarize the diagnostic algorithm and to recommend the appropriate antibiotic therapy with respect to evidence-based medicine. The recommendations are consistent with most European guidelines as well as those published by the IDSA. The guideline provides the most recent information on the epidemiology, etiology and pathogenesis of Lyme borreliosis, dermatological, neurological and musculoskeletal involvement, the appropriate diagnostic procedure and prevention. Some information is also provided about post-treatment Lyme disease syndrome. Recommended oral and intravenous antimicrobials are listed in a table showing the doses and duration of therapy. The guideline also mentions diagnostic methods to be avoided or whose results should be interpreted with caution. Although the guideline cannot account for all individual variations among patients, it may provide instructions to physicians in typical and frequent clinical situations.
该国家指南旨在突出有关该感染临床表现的最新知识,总结诊断算法,并根据循证医学推荐适当的抗生素治疗方法。这些建议与大多数欧洲指南以及美国感染病学会(IDSA)发布的指南一致。该指南提供了有关莱姆病螺旋体病的流行病学、病因学和发病机制、皮肤、神经和肌肉骨骼受累情况、适当的诊断程序及预防方面的最新信息。还提供了一些关于治疗后莱姆病综合征的信息。推荐的口服和静脉用抗菌药物列于一张表格中,显示了治疗剂量和疗程。该指南还提及了应避免使用的诊断方法或其结果应谨慎解读的方法。尽管该指南无法涵盖患者之间的所有个体差异,但它可为医生在典型和常见临床情况下提供指导。