Griffin B R, Stewart G R, Berger M S, Geyer J R, O'Dell M, Rostad S
Department of Radiation Oncology, University of Washington Hospital, Seattle.
Pediatr Neurosci. 1988;14(3):134-9. doi: 10.1159/000120378.
An 8-month-old female infant with choroid plexus carcinoma presenting in the fourth ventricle is described. The patient was initially treated with combination chemotherapy due to her young age, but developed local tumor recurrence 13 months after beginning treatment. Staging studies to detect tumor seeding of the cerebrospinal fluid were negative, and the patient received posterior fossa radiotherapy. Although the primary tumor regressed with radiation treatment, widespread disease throughout the spinal subarachnoid space subsequently developed. Choroid plexus carcinoma has a significant tendency to metastasize through the cerebrospinal fluid, and treatment of the entire neuraxis should be strongly considered for patients with this disease.
本文描述了一名8个月大的患有第四脑室脉络丛癌的女婴。由于患者年龄较小，最初接受了联合化疗，但在开始治疗13个月后出现了局部肿瘤复发。检测脑脊液中肿瘤播散的分期研究结果为阴性，患者接受了后颅窝放疗。尽管原发性肿瘤经放射治疗后消退，但随后在整个脊髓蛛网膜下腔出现了广泛的病变。脉络丛癌有通过脑脊液发生转移的显著倾向，对于患有这种疾病的患者，应强烈考虑对整个神经轴进行治疗。
