Fonseca Ricardo, Monteiro Filipa, Mendes Rita
Internal Medicine Department, Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Eur J Case Rep Intern Med. 2017 Mar 7;4(5):000594. doi: 10.12890/2017_000594. eCollection 2017.
Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is a common cause of euvolemic hyponatremia which has many possible etiologies such as tumors (mainly lung cancers). We present a case of a 79-year old women hospitalized due to microcytic anemia with transfusion need and hyponatremia due to SIADH. Three primary tumors without known metastasis were discovered. The case shows the importance of studying causes of hyponatremia.
Hyponatremia is a common electrolytic disorder during hospitalization and is associated with greater mortality.Correction of hyponatremia, cause can be devastating unless the underlying causes are investigated as it can be caused by severe diseases.Cancer must be excluded in the absence of an obvious etiology of SIADH (drugs, pulmonary and nervous system disorders).
抗利尿激素分泌异常综合征(SIADH)是等渗性低钠血症的常见病因,其有多种可能的病因,如肿瘤(主要是肺癌)。我们报告一例79岁女性因小细胞贫血需要输血以及因SIADH导致低钠血症而住院的病例。发现了三处无已知转移的原发性肿瘤。该病例显示了研究低钠血症病因的重要性。
低钠血症是住院期间常见的电解质紊乱,且与更高的死亡率相关。除非对潜在病因进行调查,否则纠正低钠血症的病因可能是灾难性的,因为它可能由严重疾病引起。在没有明显的SIADH病因(药物、肺部和神经系统疾病)时,必须排除癌症。