Perry Martin Edward, Cooper Sarah, Corry Shona
Department of Rheumatology, Royal Alexandra Hospital, Paisley, UK.
Undergraduate Medical School, University of Glasgow, Glasgow, UK.
Eur J Case Rep Intern Med. 2017 Sep 5;4(9):000718. doi: 10.12890/2017_000718. eCollection 2017.
Syphilis is one of the oldest described infectious diseases in the world and is caused by the spirochete bacterium . Although now a rare disease, incidence is increasing with the number of diagnoses of the disease rising in England from 1688 to 2713 between 2003 and 2012 (a 61% increase). Major outbreaks of syphilis have been documented in London, Manchester, Dublin, and Brighton particularly among men who have sex with men (MSM). Diagnosis remains difficult on account of multi-system symptoms, duration of the condition, and social stigma.
Normal CSF pressure with indistinct optic disc margins suggests papillitis, not papilloedemaNeurosyphilis can cause various ocular symptoms and is a cause of unexplained high ESRWhen treating with penicillin, the physician should be aware of a potential Jarish-Herzheimer reaction.
梅毒是世界上描述最古老的传染病之一，由螺旋体细菌引起。虽然现在是一种罕见疾病，但发病率正在上升，2003年至2012年间英格兰梅毒诊断病例数从1688例增至2713例（增长61%）。伦敦、曼彻斯特、都柏林和布莱顿记录了梅毒的主要暴发，特别是在男男性行为者（MSM）中。由于多系统症状、病情持续时间和社会耻辱感，诊断仍然困难。
脑脊液压力正常且视盘边缘不清晰提示为视乳头炎，而非视乳头水肿
神经梅毒可引起各种眼部症状，是血沉升高原因不明的一个病因
使用青霉素治疗时，医生应注意可能发生的赫氏反应。
